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All Journal Asian Australasian Neuro and Health Science Journal (AANHS-J) Jurnal Neuroanestesi Indonesia
Indharty, R. R. Suzy
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Biochemistry, Genetics & Molecular Biology Education Health Professions Medicine & Pharmacology Neuroscience Public Health

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Correlation Between Sleep Patterns and Blood Pressure in Students of Universitas Prima Indonesia Yang, Jason; Bob Haykal, Teuku; Barus, Melvin Nova Gunawanto; Indharty, R. R. Suzy
Asian Australasian Neuro and Health Science Journal (AANHS-J) Vol. 6 No. 1 (2024): AANHS Journal
Publisher : Talenta Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/aanhsj.v6i1.15017

Abstract

Introduction: Hypertension is a chronic condition which blood pressure increases above normal limits. It can cause a variety of other health issues such as heart, eyes, and kidney problems. Hypertension can occur due to various risk factors such as sleep disturbance. Sleep disturbance often occurs in students that could be affected by demands from college such as attending school community, school tasks, or exams. Objective: Correlation between sleep patterns and blood pressure in students of the Faculty of Medicine, Universitas Prima Indonesia in 2023. Method: Cross-sectional, the samples in this study are students of the Faculty of Medicine, Universitas Prima Indonesia, Class 2020-2022 who had met the selection and exclusion criteria based on the quota sampling technique. The data was then analyzed with the Chi-Square test. Result: The calculation results show that out of 85 respondents, 49 people (57,6%) had poor sleep patterns and 36 people (42,9%) had good sleep patterns. Out of 85 respondents, 11 people (12,9%) had normal blood pressure, 35 people (41,2%) had pre-hypertension blood pressure, 33 people (38,8%) had stage 1 hypertension blood pressure, and 6 people (7,1%) had stage 2 hypertension blood pressure. The Chi-Square test results showed no meaningful relationship between sleep patterns and blood pressure (p value=0,929). Conclusion: There is no meaningful relationship between sleep patterns and blood pressure of Universitas Prima Indonesia students in 2023. Keywords: blood pressure, hypertension, sleep patterns
Cerebral Perfusion Pressure in Traumatic Brain Injury: A Dynamic Battlefield of Flow and Pressure Primanov, Rama Mahardika; Putri Maharani, Dinda; Maria Situmorang, Ruth; Indharty, R. R. Suzy; Marolop Pangihutan, Andre
Jurnal Neuroanestesi Indonesia Vol 15, No 1 (2026)
Publisher : https://snacc.org/wp-content/uploads/2019/fall/Intl-news3.html

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24244/jni.v15i1.668

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Introduction: Traumatic brain injury (TBI) affects 27-69 million people annually, with over 55 million living with long-term disability. A major management challenge is disruption of cerebral autoregulation, a mechanism that maintains stable cerebral blood flow (CBF) despite systemic pressure changes. Impaired cerebral perfusion pressure (CPP) autoregulation promotes ischemia, edema, and metabolic imbalance, worsening neurological outcomes. Method: This narrative review synthesized literature from PubMed, Google Scholar, ScienceDirect, and the Cochrane Library, focusing on studies from the past decade. Keywords included “cerebral perfusion pressure,” “autoregulation,” “traumatic brain injury,” “TBI,” “mechanism,” “pressure reactivity index,” and “monitoring.” Discussion: TBI-related autoregulation impairment stems from vascular injury, inflammation, and myogenic dysfunction, with patterns ranging from intact to delayed or absent responses. The pressure reactivity index (PRx) enables continuous autoregulation assessment and determination of patient-specific optimal CPP (CPPopt). Observational data link maintaining CPP near CPPopt with better outcomes, while time below CPPopt increases mortality risk. Experimental models identify endothelin-1, ERK1/2, and interleukin-6 as key mediators, with targeted interventions showing potential to preserve reactivity. Conclusion: Integrating mechanistic insights with invasive monitoring and PRx-guided CPP optimization offers a promising, individualized strategy for TBI care, warranting confirmation in large clinical trials.
Co-Authors Barus, Melvin Nova Gunawanto Maria Situmorang, Ruth Marolop Pangihutan, Andre Primanov, Rama Mahardika Putri Maharani, Dinda Teuku Bob Haykal Yang, Jason