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Nutrients, Phytochemical, Antioxidant and Antimicrobial Analysis of Pterocarpus osun Stem Bark and Leaf for Their Nutritional, Medicinal Capacity Fadeyi, Adewale Elijah; Adeniran, Oluremi Isola; Akiode, Saheed Olatunbosun
Indonesian Journal of Chemical Research Vol 10 No 1 (2022): Edition for May 2022
Publisher : Jurusan Kimia, Fakultas Sains dan Teknologi, Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598/ijcr.2022.10-ade

Abstract

Plants play a crucial role in human well-being and health. They provide some of the essential nutrients that humans require as well as act as medications to alleviate and cure various health problems. The purpose of this study is to look into the nutritional value, mineral composition, and the overall contributions of Pterocarpus osun to human nutrition and health. The result of the proximate analysis showed that protein is 9.52% in stem bark and 13.63% in the leaf, while the crude fiber in the stem bark is 37.89% and 46.03%, in the leaf. Ash, 6.74% and 7.46% in the stem bark and leaf respectively while carbohydrate content is 15.37% (stem bark) and 3.26% (leaf). Alkaloids, flavonoids, terpenoids, steroids, and tannins were detected in both organs of the plant tested. The mineral elements present include Ca, Mn, Fe, Ni, Mg, Zn, Cr, Co, Cd, Sulphur, and phosphorus. The antioxidant effect compared favorably well with that of the ascorbic acid used as standard. The extracts were screened for antimicrobial activities using eleven human pathogens. Each of the extracts successfully killed six microbes.
Bioprospective screening and characterization of isolates from Pterocarpus osun leaf and stem bark extracts Fadeyi, Adewale Elijah; Afolayan, Michael Olalekan; Adeniran, Oluremi Isola
Indonesian Journal of Chemical Research Vol 11 No 2 (2023): Edition for September 2023
Publisher : Jurusan Kimia, Fakultas Sains dan Teknologi, Universitas Pattimura

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30598//ijcr.2023.11-ade

Abstract

Antimicrobial resistance (AMR) ranks among the top 10 world health challenges of the 21st century, predicted that it will cause approximately 10 million deaths in 2050. Therefore, more investigation into identifying new antibiotics from natural sources is inevitable. Compounds from the leaf and stem bark of Pterocarpus osun were isolated using column chromatography, screened for their bioactivities, and characterized using the FTIR spectroscopy method in the ongoing search for novel antimicrobial therapies. The isolates were tested for antibacterial and antifungal activities against eleven pathogenic organisms. The zones of inhibition ranged in diameter from 22 to 30 mm. The minimum inhibitory concentrations were determined. Thin-layer chromatography was used to determine the purity of the compounds, and their retention factor was calculated. This ranged between 0.2424 and 0.8151. The melting points of the compounds were also recorded, as are FTIR spectra ranging from 4000 to 400 cm-1. Some of the peaks recorded are typical of single bond (4000-25000 cm-1), double bond (2000-1500 cm-1) with confirmation in the fingerprint (1500-400 cm-1) region but none in the triple bond (2500-2000 cm-1) region of the spectra. The antimicrobial screening results show that the identified compounds can potentially lead to the discovery of novel antibiotic medications.