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All Journal SCRIPTA SCORE Scientific Medical Journal Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Pase, Muhammad Aron
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Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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A Correlational Study Elevated Risk of Cardiometabolic Illness and the Prevalence of Obstructive Sleep Apnea Among the Population of Tebing Tinggi, North Sumatra, Indonesia Raynaldo, Abdul Halim; Pase, Muhammad Aron; Ketaren, Andre Pasha
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 5 No. 3 (2023): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v5i3.14330

Abstract

Background: Obstructive Sleep Apnea (OSA) is a prevalent sleep-related breathing issue, marked by repeated full or partial blockages of the upper airways. It's a primary respiratory condition that heightens the chances of cardiometabolic diseases. In our research, we explored the link between the increased risk of cardiometabolic ailments and the potential for OSA. Method: We studied 75 participants during community service activities and investigated the association between the high risk of cardiometabolic disease and the risk of OSA in the Society of Tebing Tinggi. We measured variables such as gender, age, weight, height, Body Mass Index (BMI), blood pressure, heart rate, random blood glucose, waist and neck circumference, and total cholesterol. Subsequently, we categorized the data and performed chi-square tests to analyze the associations between various factors and the risk of OSA. Variables with p<0.05 are considered eligible for multivariate analysis using binary logistic regression. Results: We identified 42 patients had a high risk of OSA (59.2%), while 33 patients had a low risk (40.8%). The study identified significant links between OSA risk and gender, age, blood pressure, and neck circumference (p-values <0.001, <0.001, and 0.01 respectively). In contrast, BMI, heart rate, glucose levels, waist size, and cholesterol did not show a significant connection to OSA risk. This indicates that while certain factors like gender, certain age groups, hypertension, and neck size are important in assessing OSA risk. However, BMI, heart rate, random blood glucose, waist circumference, and total cholesterol are not significant factors in determining the risk of OSA (p=0.2, p=0.4, p=0.2, p=0.1, p=0.9). Conclusions: Higher risk of cardiometabolic diseases (older age, gender, hypertension, neck size) was positively associated with the risk of OSA.
Exclusive Breastfeeding Versus Combination Feeding on Incidence of Atopic Dermatitis: A Comparative Study Nova Zairina Lubis; Wijaya, Albert; Lubis, Hilfan Ade Putra; Pase, Muhammad Aron
SCRIPTA SCORE Scientific Medical Journal Vol. 6 No. 2 (2025): SCRIPTA SCORE Scientific Medical Journal
Publisher : Talenta Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/scripta.v6i2.17865

Abstract

Background. In spite of the extensive research on the potential protective effects of exclusive breastfeeding in preventing the occurrence of atopic dermatitis and the involvement of cow’s milk allergy as a triggering factor, controversies regarding this issue persist. Objective. This study analyzes the comparison of the incidence of AD among infants exclusively breastfed compared to those who receive a combination of formula milk and breastfeeding. Methods. This study is an analytical research with a cross-sectional approach, conducted at Puskesmas Sentosa Baru Medan in August 2023. The sample consisted of 114 infants, which divided into two groups: exclusively breastfed infants and the other consisting of infants who received a combination of breastfeeding and formula milk, selected through consecutive sampling. The diagnosis of AD was based on a questionnaire modified from the Hanifin-Rajka criteria. Results. According to the research findings, among the exclusively breastfed infants, 11 (19,3%) were found to have AD, whereas in the opposing group, there were 12 (21,1%) cases of AD. Statistical analysis indicated no significant difference in the incidence of AD based on early feeding history (p=0,815). The prevalence ratio of AD infants from both study group is 1,10. Conclusions. Infants who receive a combination of breast milk and formula feeding have an elevated risk of 1,1 times for the onset of AD compared to those who are exclusively breastfed. There is no significant difference in the incidence of AD among infants who are exclusively breastfed and those who receive a combination of breast and formula feeding.   Latar belakang. Meskipun telah banyak penelitian mengenai potensi efek perlindungan ASI eksklusif dalam mencegah terjadinya dermatitis atopik dan keterlibatan alergi susu sapi sebagai faktor pemicu, kontroversi mengenai hal ini masih terus berlanjut. Tujuan. Penelitian ini bertujuan untuk menganalisis perbandingan kejadian DA pada bayi yang mendapat ASI eksklusif dibandingkan dengan bayi yang mendapat kombinasi susu formula dan ASI. Metode. Penelitian ini merupakan penelitian analitik dengan pendekatan potong lintang, yang dilakukan di Puskesmas Sentosa Baru Medan pada bulan Agustus 2023. Sampel terdiri dari 114 bayi, yang dibagi menjadi dua kelompok yaitu bayi yang diberi ASI eksklusif dan bayi yang diberi kombinasi ASI dan susu formula, yang dipilih secara consecutive sampling. Selanjutnya, diagnosis DA didasarkan pada kuesioner yang dimodifikasi dari kriteria Hanifin-Rajka. Hasil. Menurut temuan penelitian, di antara bayi yang disusui secara eksklusif, 11 (19,3%) ditemukan menderita DA, sedangkan pada kelompok yang tidak disusui, terdapat 12 (21,1%) kasus DA. Analisis statistik menunjukkan tidak ada perbedaan yang signifikan dalam kejadian PJB berdasarkan riwayat pemberian makanan awal (p=0,815). Rasio prevalensi bayi AD dari kedua kelompok penelitian adalah 1,10. Kesimpulan. Bayi yang menerima kombinasi ASI dan susu formula memiliki risiko 1,1 kali lebih tinggi untuk mengalami PJB dibandingkan dengan bayi yang mendapat ASI eksklusif. Tidak ada perbedaan yang signifikan dalam kejadian DA antara bayi yang diberi ASI eksklusif dan mereka yang menerima kombinasi ASI dan susu formula.
ASSOCIATION OF TRIGLYCERIDE / HIGH-DENSITY LIPOPROTEIN RATIO (TG/HDL RATIO) TO SPECIFIC RISK FACTORS OF DIABETES AND PREDIABETES Nasution, Melati Silvanni; Pase, Muhammad Aron; Nasution, Ali Nafiah
Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI) Vol. 6 No. 4 (2024): Journal of Endocrinology, Tropical Medicine, and Infectious Disease (JETROMI)
Publisher : TALENTA Publisher, Universitas Sumatera Utara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32734/jetromi.v6i4.17394

Abstract

Background: Diabetes is a group of metabolic diseases characterized by hyperglycemia due to defects in insulin secretion, insulin action, or both. Prediabetes is a precursor before the diagnosis of diabetes. Patients with prediabetes and diabetes have several risk factors, one of which is dyslipidemia. The TG/HDL ratio is found to be positively associated with insulin resistance and CVD. This study was conducted to determine whether there is a relationship between TG/HDL ratio and the incidence of prediabetes and diabetes. Method: This analytic cross-sectional study was conducted on July-December 2023. The study samples were prediabetic and diabetic patients who met the acceptance criteria of the study subjects. They were tested for BMI, BG, HbA1C and lipid profile. Data analysis used paired t test and Pearson correlation Result: In this study, BMI was greater in the prediabetes group than the diabetes group. There was a negative correlation between age, BG and HDL levels on TG/HDL ratio in prediabetic and diabetic patients. There was a significant relationship between fasting BG, 2 hours after meals BG, HbA1C and TG/HDL ratio when compared between the prediabetes and the diabetes group. Conclusion: In this study, there was no association between TG/HDL ratio in prediabetes and diabetes. Keywords: Prediabetes, diabetes, TG, HDL, HbA1c
Co-Authors Albert Wijaya Ketaren, Andre Pasha Lubis, Hilfan Ade Putra Nasution, Ali Nafiah Nasution, Melati Silvanni Nova Zairina Lubis Raynaldo, Abdul Halim