Article Per Year (5 Year)
p-Index From 2020 - 2025
0.23
P-Index
This Author published in this journals
All Journal JOPS (Journal Of Pharmacy and Science)
Assyfa, Dini
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
MSC Secretome's Antibacterial Activity on P. aeruginosa Isolated from Diabetic Ulcer Patient Assyfa, Dini; Marlina, Marlina; Djamaan, Akmal
JURNAL FARMASI DAN MAKANAN Vol 7 No 2 (2024): Journal of Pharmacy and Science
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/jops.v7i2.4717

Abstract

The study aims to determine the antibacterial activity of adipose tissue-derived Mesenchymal Stem Cell (MSC) secretome against P. aeruginosa bacteria isolated from diabetic ulcer patients. Bacteria were isolated from specimens obtained from diabetic ulcer patient and identified using MacConkey and Blood Agar media followed by Polymerase Chain Reaction (PCR) molecular identification. Confirmed P. aeruginosa bacteria were used to evaluate the MSC secretome's antibacterial activity via the Kirby-Bauer method. Isolated bacteria grew on MacConkey media as gram-negative, non-lactose-fermenting bacteria, showing hemolytic capabilities on Blood Agar media. PCR identification yielded positive results for P. aeruginosa. In antibacterial activity testing against isolated bacteria, MSC secretome at concentrations of 1.25%, 2.5%, 5%, and 10% exhibited efficacy with average inhibitory zones measuring 8.17 mm, 8.23 mm, 8.52 mm, and 9.30 mm, respectively. The MSC secretome demonstrates antibacterial activity against P. aeruginosa bacteria isolated from diabetic ulcer patients.
Co-Authors Akmal Djamaan Marlina Marlina