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Fakhrul Akbar Arrahim
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Aktivitas Antibakteri Ekstrak Etanol Buah Alkesa terhadap S. aureus dan E. coli Fakhrul Akbar Arrahim; Vinda Maharani Patricia; Livia Syafnir
Jurnal Riset Farmasi Volume 4, No. 1, Juli 2024, Jurnal Riset Farmasi (JRF)
Publisher : UPT Publikasi Ilmiah Unisba

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29313/jrf.v4i1.3891

Abstract

Abstract. Alkesa fruit (Pouteria campechiana (Kunth) Baehni) has many benefits, one of which is suspected to possess pharmacological activity as an antibacterial agent. Staphylococcus aureus and Escherichia coli are pathogenic bacteria that commonly cause diseases in humans, such as diarrhea. The aims of this study was to determine the antibacterial activity of the ethanol extract of alkesa fruit against Staphylococcus aureus and Escherichia coli, as well as to determine the Minimum Inhibitory Concentration (MIC). The antibacterial activity test was conducted using the agar diffusion method with ethanol extract of alkesa fruit at concentrations ranging from 35% to 100% (w/v). The results showed that the ethanol extract of alkesa fruit exhibited the same level of activity against both bacteria, with the same minimum inhibitory concentration, which is 36%. Abstrak. Buah alkesa (Pouteria campechiana (Kunth) Baehni) memiliki banyak manfaat yang salah satunya diduga memiliki aktivitas farmakologi sebagai antibakteri. Bakteri Staphylococcus aureus dan Escherichia coli merupakan bakteri patogen yang biasanya menimbulkan penyakit pada manusia contohnya yaitu penyakit diare. Tujuan penelitian ini untuk mengetahui aktivitas antibakteri ekstrak etanol buah alkesa terhadap Staphylococcus aureus dan Escherichia coli serta menentukan Konsentrasi Hambat Minimum. Pengujian aktivitas antibakteri dilakukan dengan metode difusi agar sumuran menggunakan ekstrak etanol buah alkesa dengan rentang konsentrasi 35% - 100% (b/v). Hasil pengujian menunjukkan bahwa ekstrak etanol buah alkesa memiliki aktivitas  yang sama terhadap kedua bakteri dengan konsentrasi hambat minimum yang sama yaitu 36%.