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Evaluating the economic screening of cervical cancer using IVA, HPV DNA, and histology methods: Systematic review Rofika, Ana; Ratnasari , Desi; Christiana , Indah; Siti Fatimah, Okta Zenita; ST. Mukarromah; Mufdillah; Listiani , Putri
Journal of Health Technology Assessment in Midwifery Vol. 6 No. 2 (2023): November
Publisher : Universitas Aisyiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31101/jhtam.3255

Abstract

Background: Cervical cancer is a common malignancy causing cancer-related deaths worldwide. Evidence suggests that adequate screening can reduce cervical cancer-related deaths. Screening for cervical cancer can be done using Visual Inspection of Acetic Acid (VIA), HPV DNA and cytology. The economic burden of cancer patients is substantial ranging from US$8,066 to 22,888 per patient. Health cost effectiveness was comparative in the analysis of costs and consequences for the three screening methods. VIA is the most cost-effective primary screening test for cervical cancer. Purpose: To review the research results of a full economic evaluation to encourage the specific cervical cancer screening methods used to enhance the detection of precancerous lesions in women's cervix. Method: This systematic review used the PRISMA ScR framework with a literature search using 3 databases, namely Pubmed, Wiley, and Google Scholar, with years of publication from 2009 – 2023. The data that has been obtained is carried out by critical appraisal using the Consolidated Health Economic Evaluation Reporting Standards (CHEERS). Results: Based on the search for 3,973 selected articles, 7 match the inclusion criteria. This systematic review discovered three major themes: the utility value of health status, cost and analysis. Conclusion: The most cost-effective cervical cancer screening is by VIA. HPV DNA and pap smear based cytology techniques have been reported to show high sensitivity and specificity respectively including being expensive and resource intensive. In contrast the VIA technique has moderate sensitivity and specificity but is less expensive Various developed countries have used Pap or HPV DNA cytology tests as the main screening method, which can lead to a 50-70% reduction in cervical cancer incidence, while in developing countries using VIA tests as a cervical cancer screening method.
REVIEW ARTIKEL : PERBANDINGAN JENIS BAHAN PENGIKAT PADA FORMULASI TABLET KUNYAH Putri Diar Faizah, Nadya; Fila Ila El Kodar, Indah; Rahmati, Dewi; Mellyana, Hanifah; Idawati Sofia, Armelia; Regita Faradila, Arina; Rindianti, Nolia; Ratnasari , Desi
JURNAL PHARMA BHAKTA Vol 5 No 1 (2025): Mei 2025
Publisher : FACULTY OF PHARMACY, INSTITUT ILMU KESEHATAN BHAKTI WIYATA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.56710/jpb.v5i1.135

Abstract

Latar belakang: Tablet merupakan bentuk sediaan padat yang mengandung bahan aktif serta bahan lain. Tablet dapat hadir dalam bentuk yang tidak dilapisi atau dilapisi. Tablet yang tidak dilapisi mencakup tablet yang bisa dikunyah, tablet yang menghasilkan gelembung, tablet hisap, tablet yang mudah larut, dan tablet yang ditempatkan di bawah lidah. Tablet kunyah diproduksi melalui proses pemadatan, biasanya memanfaatkan manitol, sorbitol, sukrosa, dan dekstrosa sebagai bahan pengisi dan pengikat, serta mengandung zat pewarna dan perasa untuk meningkatkan tampilan dan cita rasa. Tujuan: berfungsi untuk meningkatkan pemahaman yang lebih baik mengenai bahan pengisi yang baik pada tablet kunyah sehingga dapat menghasilkan produk obat yang baik. Metode: literatur review article. Kesimpulan: Berdasarkan data yang telah dikumpulkan terkait dengan bahan pengikat sediaan tablet kunyah dapat disimpulkan bahwa setiap bahan pengikat memiliki keunggulan tersendiri dan pemilihan bahan harus disesuaikan dengan karakteristik bahan aktif yang digunakan, serta kriteria fisik seperti kekerasan, kerapuhan, dan waktu hancur.