Article Per Year (5 Year)
p-Index From 2020 - 2025
0.61
P-Index
This Author published in this journals
All Journal IJNP (Indonesian Journal of Nursing Practices) Journal of Nursing Practice and Education
Rahayuningrat, Nurunnisa
Unknown Affiliation
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health

Published : 3 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search

 1 
Empowering Natural Medicine: Combining Brotowali Extract (T.Crispa) with Lampung Natural Zeolite to Improve Diabetic Wound Healing Mulyati, Lia; Wulandari, Afni; Devi, Fitria Kusuma; Rahayuningrat, Nurunnisa
IJNP (Indonesian Journal of Nursing Practices) Vol 8, No 1 (2024): June
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/ijnp.v8i1.19586

Abstract

Background: Diabetic ulcers are a serious complication that often occurs in people with diabetes mellitus. The complication leads to amputation and causes disability in about 30% of patients.Objective: The study aims to test the effectiveness of an ointment formulation containing brotowali extract with a combination of Lampung natural zeolite (ZAL) in the healing process of diabetic ulcers.Methods: The research method used is quasi-experimental with a control group. The sample of this study used mice, with a total of 6 in each group. Before the intervention, blood sugar levels in the samples were increased by injecting streptozotocin. The study was conducted for 14 days. The Mann-Whitney test was used to analyze the data obtained.Results: The results showed a significant difference in the percentage of wound closure between the control group and the intervention group with p=0.002.Conclusion: Based on these findings, it can be concluded that an ointment formulation containing brotowali extract with a combination of ZAL effectively accelerates the wound healing process in diabetic mice.  Brotowali extract ointment with a combination of Lampung natural zeolites can be used as an alternative in wound care for patients with diabetes mellitus based on herbs and local wisdom so that it will be more easily accepted in the community.
Pengaruh salep formulasi ekstrak brotowali dengan kombinasi zeolite alam lampung terhadap penyembuhan ulkus diabetik Wulandari, Afni; Rahayuningrat, Nurunnisa; Kusuma Devi, Pitria; Mulyati, Lia; Hermansyah, Heri
Jurnal Praktik Dan Pendidikan Keperawatan Vol 4 No 1 (2023): Journal of Nursing Practice and Education
Publisher : Lembaga Penelitian Sekolah Tinggi Ilmu Kesehatan Garawangi

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34305/jnpe.v4i1.836

Abstract

Latar Belakang: Komplikasi ini dapat menyebabkan amputasi dan kecacatan pada sekitar 30% penderita. Penelitian ini bertujuan untuk mengevaluasi pengaruh salep formulasi ekstrak brotowali dengan kombinasi zeolite alam Lampung (ZAL) terhadap penyembuhan ulkus diabetikum.Metode: Penelitian ini merupakan penelitian quasi eksperimen, one grup pre-post test, sampel penelitian adalah mencit berumur 2-3 bulan dengan BB 25-40 gram sebanyak 12 ekor yang sudah di suntik streptozotocin untuk membuat kondisi hiperglikemi. Hasil  pengamatan di analisis dengan menggunakan tendensi central untuk data univariat dan uji wilcoxon untuk bivariat.Hasil: Menunjukkan adanya perbedaan signifikan pada luas luka sebelum dan setelah dilakukan perawatan dengan menggunakan salep ekstrak brotowali dengan kombinasi zeolite alam Lampung. Rata-rata luas luka sebelum perawatan adalah 1.00 mm dengan standar deviasi 0.16, sedangkan setelah perawatan luas luka menurun menjadi 0.02 mm dengan standar deviasi 0.03. Hasil analisis bivariat didapatkan p value 0.002 dengan mean negatif rank 6.50.Kesimpulan: Penggunaan salep ekstrak brotowali dengan kombinasi ZAL secara efektif berkontribusi dalam penyembuhan luka diabetes pada ulkus diabetikum.
Empowering Natural Medicine: Combining Brotowali Extract (T.Crispa) with Lampung Natural Zeolite to Improve Diabetic Wound Healing Mulyati, Lia; Wulandari, Afni; Devi, Fitria Kusuma; Rahayuningrat, Nurunnisa
IJNP (Indonesian Journal of Nursing Practices) Vol. 8 No. 1 (2024): June
Publisher : Universitas Muhammadiyah Yogyakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18196/ijnp.v8i1.19586

Abstract

Background: Diabetic ulcers are a serious complication that often occurs in people with diabetes mellitus. The complication leads to amputation and causes disability in about 30% of patients.Objective: The study aims to test the effectiveness of an ointment formulation containing brotowali extract with a combination of Lampung natural zeolite (ZAL) in the healing process of diabetic ulcers.Methods: The research method used is quasi-experimental with a control group. The sample of this study used mice, with a total of 6 in each group. Before the intervention, blood sugar levels in the samples were increased by injecting streptozotocin. The study was conducted for 14 days. The Mann-Whitney test was used to analyze the data obtained.Results: The results showed a significant difference in the percentage of wound closure between the control group and the intervention group with p=0.002.Conclusion: Based on these findings, it can be concluded that an ointment formulation containing brotowali extract with a combination of ZAL effectively accelerates the wound healing process in diabetic mice.  Brotowali extract ointment with a combination of Lampung natural zeolites can be used as an alternative in wound care for patients with diabetes mellitus based on herbs and local wisdom so that it will be more easily accepted in the community.
Co-Authors Devi, Fitria Kusuma Heri Hermansyah Kusuma Devi, Pitria Mulyati, Lia Wulandari, Afni