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All Journal SAINS MEDIKA : JURNAL KEDOKTERAN DAN KESEHATAN Diponegoro International Medical Journal (DIMJ)
Raharjo, Rudi Yuwono
Unknown Affiliation
Health Professions Medicine & Pharmacology Neuroscience

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Malnutrition and Developmental Delay Presenting as Complications of Late Onset Hirschprung’s disease : A Case Report Pujiati, Pujiati; Raharjo, Rudi Yuwono; Ovaditya, Shafira Zahra
Diponegoro International Medical Journal Vol 4, No 1 (2023): July 2023
Publisher : Faculty of Medicine, Diponegoro University

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.14710/dimj.v4i1.17842

Abstract

Background: Hirschsprung’s Disease is a congenital disorder characterized by the absence of ganglionic cells in the colon, causing loss of peristaltic movement in the bowel. Most cases are diagnosed before the age of one and marked by the delayed passage of meconium, vomiting, and distended abdomen. Here, we present a case of a 2-year-old boy with an atypical presentation of malnutrition and developmental delay as a complication of Hirschsprung’s Disease. Case Presentation: A 2-year-old boy who presented with abdominal distention and chronic constipation was referred to our hospital. Past personal history revealed that he frequently suffered from the symptoms but was previously diagnosed with regular constipation and only consumed symptomatic medication. On admission, his vital signs were all normal, but his appearance was pale and weak. Growth and developmental screening showed poor growth status and developmental delay in all four domains. From the physical examination, gross abdominal distention was found and the rectal examination demonstrated a tight anal sphincter, empty rectal vault, and a green-colored stool with no forceful expulsion. Radiologic and histopathological findings suggested Hirschsprung’s disease. Conclusion: Chronic abdominal distention followed by malnutrition and developmental delay can present as a complication of hirschsprung’s diseasein older children. Due to these subtle signs and symptoms, a thorough examination and proper diagnostic algorithm are
Clinical and epidemiological characteristics of pediatric solid tumours at Sultan Agung Islamic Hospital (2018–2023) Mayangsari, Citra Primavita; Raharjo, Rudi Yuwono; Ardelia, Alinda; Pramudya, Raihan Daffa Setiyo
Sains Medika: Jurnal Kedokteran dan Kesehatan Vol 16, No 1 (2025): June 2025
Publisher : Faculty of Medicine, Universitas Islam Sultan Agung (UNISSULA), Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.30659/sainsmed.v16i1.39770

Abstract

A tumour is an abnormal mass of tissue that does not contain cysts or fluid. According to the Global Cancer Statistics, approximately 275,000 children worldwide were diagnosed with cancer in 2022. Among pediatric solid tumours, the most common types include neuroblastoma, rhabdomyosarcoma, retinoblastoma, osteosarcoma, and Ewing sarcoma. This study aims to analyse the prevalence and characteristics of solid tumours in children treated at Sultan Agung Islamic Hospital in Semarang. A descriptive quantitative approach was employed, utilising retrospective data from medical records. The study population comprised pediatric inpatients and outpatients aged 0 to 17 years who underwent pathological or radiological examinations between 2018 and 2024. Data analysed included demographic details (age, gender), presenting symptoms, and blood test results. The study identified 22 pediatric patients with solid tumours, with Rhabdomyosarcoma and Teratoma being the most common types. The gender distribution was evenly split between males and females. Notably, 73% of the patients showed recovery. Common presenting symptoms included palpable lumps (45%) and pain (41%). Blood tests revealed that haemoglobin levels in children aged 2-9 years were below the usual lower limit (8.21 ± 4.88 g/dL). White blood cell counts in the same age group were abnormal, averaging 11.20 ± 8.36  103/µL. Platelet counts across the age span of 1 month to 17 years were elevated, with a mean of 412.33 ± 224.11 103/µL. In conclusion, the supporting laboratory examinations frequently indicated anaemia, leukocytosis, and thrombocytosis among pediatric tumour patients. These findings underscore the importance of comprehensive diagnostic assessments in managing pediatric solid tumours.
Co-Authors Ardelia, Alinda Heni Pujiastuti Mayangsari, Citra Primavita Ovaditya, Shafira Zahra Pramudya, Raihan Daffa Setiyo