Article Per Year (5 Year)
p-Index From 2021 - 2026
0.408
P-Index
This Author published in this journals
All Journal Molecular and Cellular Biomedical Sciences (MCBS) CRJIM (Clinical and Research Journal in Internal Medicine)
Singh, Puja
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Dentistry Education Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing Public Health Other

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Correlation between Yokohama Cytological Coding and Radiological Findings and Their Diagnostic Accuracies against Histopathology: A Retrospective Study of Palpable Breast Lesions Singh, Puja; Badlani, Bharti; Dehariya, Chanchalesh; Joher, Munira Murtaza
Molecular and Cellular Biomedical Sciences Vol 8, No 2 (2024)
Publisher : Cell and BioPharmaceutical Institute

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21705/mcbs.v8i2.439

Abstract

Background: Breast carcinoma is the most common malignancy and demands quick and accurate diagnosis and treatment. Precise diagnosis of breast lesions is made using a triple-test approach: clinical, radiological and cytological. However, multiple steps make the process time-consuming and expensive. In developing countries like India, trained and certified radiologists are extremely overburdened. Fine needle aspiration cytology (FNAC) along with clinical examination can fill the gap. This study aims to correlate cytological, radiological and histological findings and measure their relative accuracies. Based on these findings, a new approach will be proposed to address the above shortcomings.Materials and methods: The FNAC was performed on all cases and reported as per Yokohama cytology. The cytological findings were correlated & validated against radiological and histopathological findings respectively. Relative performance of cytological and radiological findings were established using sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy. A chi-square test for independence between cytological and radiological findings was performed.Results: The sensitivity, specificity, PPV, NPV, and accuracy for cytological findings come out as 97.60, 90.08, 90.37, 97.52, and 93.75, respectively. Meanwhile, the Radiological findings come out as 96.61, 82.20, 84.44, 96.04, and 89.41, respectively. The chi-square test demonstrates strong interdependence between cytological and radiological findings.Conclusion: FNAC is more accurate, quicker, and cheaper than radiological tests. Hence, FNAC based on the Yokohama system, along with clinical observations, can be used as a primary diagnosis tool in developing countries with limited health resources without making significant compromises on incorrect treatment. If needed, radiology and histopathology can be used for precise diagnosis and treatment.Keywords: FNAC, cytology, breast lesions, Yokohama, radiology, histopathology
Unraveling the Complexities of Severe Dengue: Exploring Transfusion Avoidance Strategies with Management of Hematological, Radiological Parameters, Clinical Features : Blood transfusion avoidance Strategies in severe dengue patients Singh, Ranbeer; Singh, Chhaviraj; Singh, Swati; Singh, Puja
Clinical and Research Journal in Internal Medicine Vol. 5 No. 2 (2024): Volume 5 No 2, November 2024
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.crjim.2024.005.02.09

Abstract

Background: Dengue is an entity caused by mosquito bites in humans. It can change into a life-threatening entity within a very short time. Not every dengue case requires a blood transfusion. While plasma leakage and a drop in platelet count are possible side effects of severe dengue, not all patients suffer from them. The main goals of treatment are to control symptoms such as pain, fever, and dehydration by giving patients enough fluids and medicine. Aim: To identify the various clinical features associated with dengue along with the manifestations not warranting blood transfusion. Methods: This observational study includes a total of 300 laboratory-verified dengue patients who were admitted over two months. Patients with other causes of fever were excluded. Results: The majority of patients (80%) were discovered to be between the ages of 10 and 40, indicating that people in this age bracket are often more afflicted. Males were predominantly affected in comparison to females. Thrombocytopenia is the most prevalent anomaly, present in all the patients. Of these, 3.0 (1.0%) had platelet counts < 10,000/cmm, while 198 (66%) had platelet levels < 10,000–20,000/cmm. Conclusion:  We conclude that the main factors influencing the prognosis are intra-abdominal visceral oedema as gall bladder wall edema, leucopenia (TLC count below 2000 cells/cmm), deranged liver functions, capillary leakage leading to peritoneal/pleural effusions as well as shock, and platelets. Platelets do not determine the severity and fatality of dengue infection.
Co-Authors Badlani, Bharti Dehariya, Chanchalesh Joher, Munira Murtaza Singh, Chhaviraj Singh, Ranbeer Singh, Swati