Article Per Year (5 Year)
p-Index From 2020 - 2025
0.61
P-Index
This Author published in this journals
All Journal Oto Rhino Laryngologica Indonesiana Eduvest - Journal of Universal Studies
Setiawathi, Ni Putu
Unknown Affiliation
Aerospace Engineering Computer Science & IT Health Professions Medicine & Pharmacology Neuroscience Social Sciences

Published : 3 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 3 Documents
Search

 1 
Hypertonic Saline Nasal Irrigation for Chronic Sinusitis: A Systematic Review and Meta-analysis Lao, Alexsandro; Vatvani, Akhil; Setiawathi, Ni Putu
Oto Rhino Laryngologica Indonesiana Vol. 53 No. 2 (2023): VOLUME 53, NO. 2 JULY - DECEMBER 2023
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32637/orli.v53i2.631

Abstract

Background: Chronic rhinosinusitis (CRS) is an inflammatory condition of the paranasal sinusescharacterized by persistent sinonasal symptoms. It is a prevalent chronic medical ailment worldwide,impacting individuals of all ages and impairs patients’ quality of life. Recent findings in otorhinolaryngology reveal that hypertonic saline nasal irrigation is more effective than isotonic saline for addressing this condition. Hypertonic saline with higher osmotic pressure demonstrates superior efficacy in reducing mucosal edema. Purpose: To study the efficacy of nasal irrigation with hypertonic saline on chronicrhinosinusitis. Literature review: Conducted following the Preferred Reporting Items for SystematicReview and Meta-Analysis (PRISMA) 2020 guidelines. The search strategy spanned prominent multipleelectronic databases (PubMed and SagePub), encompassing publications from 2015 to 2023. Duplicatepublications, review articles, and incomplete articles were excluded. A meta-analysis was planned toanalyze outcome of Visual Analog Scale (VAS) score. Result: The search results from the year 2015-2023 yielded 35 articles from PubMed and 28 articles from SagePub. In the end, 4 eligible studies wereobtained. From these, hypertonic saline demonstrated enhanced symptomatic relief. However, only twostudies were eligible for meta-analysis, revealing no significant VAS difference between hypertonic andnormal saline (mean difference 2.40 [95% CI -2.85 – 7.65]; p 0.37). Conclusion: Hypertonic saline nasal irrigation offered moderate side effects, improved nasal symptoms and ciliary activity more than isotonic saline, although there were no significant differences in radiological imaging or sense of smell. However, the meta-analysis did not find a significant difference in VAS scores.Keywords: chronic rhinosinusitis, ciliary activity, nasal irrigation, hypertonic saline
Clinical and Histopathological Profile of Nasopharyngeal Carcinoma Patients in the Department of Otolaryngology-Head and Neck Surgery at Prof. Dr. I.G.N.G. Ngoerah General Hospital in 2022 – 2024 Diahswari Widyadari, Kadek Santi; Setiawathi, Ni Putu; Widiantari, Ida Ayu Alit
Eduvest - Journal of Universal Studies Vol. 5 No. 10 (2025): Eduvest - Journal of Universal Studies
Publisher : Green Publisher Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59188/eduvest.v5i10.52179

Abstract

Backgrounds: Nasopharyngeal carcinoma (NPC) is a form of carcinoma of the nasopharyngeal epithelium, where NPC is 6th as the most common carcinoma in Indonesia. This research aimed to find and get to know the clinical and histopathological profile of NPC patients in the Department of Otolaryngology-Head and Neck Surgery at Prof. Dr. I.G.N.G. Ngoerah General Hospital. Methods: This study is a descriptive observational study with a cross-sectional approach, conducted to determine the clinical and histopathological profile of NPC patients. Using total sampling method, data collection was carried out in May 2025 done by observing secondary data in the form of electronic medical records. The inclusion criteria of this study were patients diagnosed with NPC, patients could be from both male or female, patients of all ages, patients that have underwent examination for staging. Results: There were 186 NPC patients in this study. Patients diagnosed with NPC are more frequent in men (69,35%), in the age group of 45-54 years (37,63%), experiencing lump in the neck (68,82%), have histopathological features of undifferentiated cell carcinoma (98,92%), most patients were in the stage IVA (39,24%). Conclusion: NPC patients come with various sociodemographic backgrounds and different clinical conditions. This study found that NPC is more frequent in men than women, commonly diagnosed in the fourth and fifth decade of life, most patients experiencing lump in the neck. This study also found that the most common histopathological features were undifferentiated cell carcinoma. Most patients were in the stage IVA.
Hypertonic Saline Nasal Irrigation for Chronic Sinusitis: A Systematic Review and Meta-analysis Lao, Alexsandro; Vatvani, Akhil; Setiawathi, Ni Putu
Oto Rhino Laryngologica Indonesiana Vol. 53 No. 2 (2023): VOLUME 53, NO. 2 JULY - DECEMBER 2023
Publisher : PERHATI-KL

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32637/orli.v53i2.631

Abstract

Background: Chronic rhinosinusitis (CRS) is an inflammatory condition of the paranasal sinusescharacterized by persistent sinonasal symptoms. It is a prevalent chronic medical ailment worldwide,impacting individuals of all ages and impairs patients’ quality of life. Recent findings in otorhinolaryngology reveal that hypertonic saline nasal irrigation is more effective than isotonic saline for addressing this condition. Hypertonic saline with higher osmotic pressure demonstrates superior efficacy in reducing mucosal edema. Purpose: To study the efficacy of nasal irrigation with hypertonic saline on chronicrhinosinusitis. Literature review: Conducted following the Preferred Reporting Items for SystematicReview and Meta-Analysis (PRISMA) 2020 guidelines. The search strategy spanned prominent multipleelectronic databases (PubMed and SagePub), encompassing publications from 2015 to 2023. Duplicatepublications, review articles, and incomplete articles were excluded. A meta-analysis was planned toanalyze outcome of Visual Analog Scale (VAS) score. Result: The search results from the year 2015-2023 yielded 35 articles from PubMed and 28 articles from SagePub. In the end, 4 eligible studies wereobtained. From these, hypertonic saline demonstrated enhanced symptomatic relief. However, only twostudies were eligible for meta-analysis, revealing no significant VAS difference between hypertonic andnormal saline (mean difference 2.40 [95% CI -2.85 – 7.65]; p 0.37). Conclusion: Hypertonic saline nasal irrigation offered moderate side effects, improved nasal symptoms and ciliary activity more than isotonic saline, although there were no significant differences in radiological imaging or sense of smell. However, the meta-analysis did not find a significant difference in VAS scores.Keywords: chronic rhinosinusitis, ciliary activity, nasal irrigation, hypertonic saline
Co-Authors Diahswari Widyadari, Kadek Santi Lao, Alexsandro Vatvani, Akhil Widiantari, Ida Ayu Alit