Article Per Year (5 Year)
p-Index From 2020 - 2025
0.444
P-Index
This Author published in this journals
All Journal Abdimas Galuh : Jurnal Pengabdian Kepada Masyarakat INDONESIAN MIDWIFERY HEALTH AND SCIENCES JOURNAL
Zahra, Larasati Az
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Economics, Econometrics & Finance Education Health Professions Immunology & microbiology Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Nursing Public Health

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search
Journal : INDONESIAN MIDWIFERY HEALTH AND SCIENCES JOURNAL

 1 
COVID-19 VACCINE DURING PREGNANCY RESULTS OF TRANSPLACENTAL ANTIBODY TRANSFER TO INFANTS AND THROUGH BREAST MILK: A LITERATURE REVIEW Zahra, Larasati Az
Indonesian Midwifery and Health Sciences Journal Vol. 9 No. 2 (2025): Indonesian Midwifery and Health Sciences Journal, April 2025
Publisher : UNIVERSITAS AIRLANGGA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/imhsj.v9i2.2025.117-135

Abstract

Background: This comprehensive literature review investigates the outcomes of administering the BNT162B2 COVID-19 vaccine during pregnancy, focusing on transmitting antibodies through both the placenta and breast milk to infants. The study evaluates existing research findings to provide a nuanced understanding of the immunological implications for newborns born to vaccinated mothers. Methods: This literature review employed the PICO method to develop the review question, focusing on studies published between 2020 and 2023, identified through PubMed, Google Scholar, ScienceDirect, and Scopus using specific keywords related to antibody transfer, COVID-19 vaccine, neonatal immunity, and pregnancy. Result: Nine articles met the inclusion criteria. The review found that COVID-19 vaccination during pregnancy promoted transplacental antibody transfer to infants and the presence of antibodies in breast milk. Conclusion: The results of this study of the literature show that administering the mRNA vaccination in the latter half or third of pregnancy boosts IgA along with IgG levels through transplacental transmission or breastfeeding. BNT162b2 vaccination of mothers in the second trimester is recommended. Breastfeeding has advantages, but limited evidence suggests significant SARS-CoV-2 antibody transfer postpartum. Prospective mothers are urged to vaccinate pre-delivery and consider breastfeeding for antibody transfer.  
Co-Authors Afifah, Dini Nur Ambarwati, Dewi Firnandani, Sherly Irwanto, Kasno Melina, Widia Rahma Sudrajat Sudrajat