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All Journal Indonesian Journal of Pharmaceutical Science and Technology Bencoolen Journal of Pharmacy
Muslimah, Annisa
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Biochemistry, Genetics & Molecular Biology Computer Science & IT Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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TINGKAT KEPATUHAN PENGGUNAAN OBAT ASMA DI APOTEK SEHAT BERSAMA 1 KOTA BENGKULU Rahmawati, Reza; Muslimah, Annisa; Banon, Charles
BENCOOLEN JOURNAL OF PHARMACY Vol. 3 No. 1 (2023): April
Publisher : UNIB PRESS

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33369/bjp.v3i1.27725

Abstract

Asma merupakan penyakit ditandai adanya inflamasi dan pembengkakan dinding dalam saluran nafas sehingga menjadi sensitif terhadap aktivitas yang berlebihan serta benda asing yang masuk dan akan menimbulkan reaksi yang berlebihan. Asma masih menjadi masalah kesehatan masyarakat hampir di semua negara, umumnya diderita oleh anak-anak hingga lansia dengan derajat penyakit dari ringan hingga berat dan bahkan beberapa kasus dapat menyebabkan kematian. Asma berdampak negatif bagi kehidupan penderitanya. Salah satu faktor yang penting dalam pengobatan asma agar terjaga kualitas hidup yang baik dan mencapai keberhasilan dalam pengobatan adalah kepatuhan pasien dalam menjalani pengobatan. Penelitian ini bertujuan untuk melakukan pengkajian tentang kepatuhan pasien asma di Apotek Sehat Bersama 1 Kota Bengkulu. Penelitian ini menggunakan desain cross sectional dan pengambilan sampel menggunakan accidental sampling dengan jumlah sampel 88 orang. Pengukuran tingkat kepatuhan menggunakan kuisioner Morisky Adherence Scale (MMAS-8). Hasil analisis statistik menunjukkan bahwa kepatuhan pasien di Apotek Sehat Bersama 1 tergolong rendah dengan frekuensi 42 orang (47.72%) sedangkan 31 orang (35.22%).
Nanoemulsion of Nagasari (Mesua ferrea L.) Leaf and Its Activity Against Staphylococus aureus Suhesti, Tuti Sri; Muslimah, Annisa
Indonesian Journal of Pharmaceutical Science and Technology Vol 12, No 2 (2025)
Publisher : Indonesian Journal of Pharmaceutical Science and Technology

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24198/ijpst.v12i2.49866

Abstract

Nagasari leaves (Mesua ferrea L.) contain special chemicals to fight S. aureus. Nanoparticle technology can improve the solubility, stability, and bioavailability of the phytochemicals found in herbal medicines. The nanoemulsion produces small particle sizes. It has a large surface area. This research aims to determine the physical stability of Nagasari leaf ethanol extract nanoemulsion (EDN) with variations of Virgin Coconut Oil (VCO) as the oil phase during storage and its activity. Nanoemulsions were produced using 1%, 2%, and 3% VCO concentrations. The physical properties and stability of the preparations were characterised. The nanoemulsion was tested for activity against S. aureus. Chloramphenicol was used as a positive control. The results showed that the nanoemulsion containing 1% VCO produced the best physical properties: a particle size of 23.137 ± 7.63 nm, a polydispersity index (PDI) of 0.203 ± 0.013, and a zeta potential of -18.9 ± 0.086. A VCO concentration of 1% produces good nanoemulsion stability. The F1 nanoemulsion exhibited an average inhibition zone diameter of 16.75 mm (strong), the EDN provided an inhibition zone diameter of 8.70 mm (medium), and the positive control exhibited an inhibition zone diameter of 24.30 mm (very strong).
Co-Authors Charles Banon Rahmawati, Reza Tuti Sri Suhesti