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All Journal Berkala Ilmu Kesehatan Kulit dan Kelamin Indonesian Journal of Electrical Engineering and Computer Science
Bansal, Shikha
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Immunology & microbiology Public Health

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System availability assessment and optimization of a series-parallel system using a genetic algorithm Chaudhary, Priya; Bansal, Shikha
Indonesian Journal of Electrical Engineering and Computer Science Vol 36, No 1: October 2024
Publisher : Institute of Advanced Engineering and Science

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.11591/ijeecs.v36.i1.pp153-162

Abstract

To optimize the operational availability of the series-parallel system and provide useful insights for maintenance planning, the study attempts to investigate the availability of a ball mill unit. These four different components make up the ball mill production system: “drum,” “ring-gear,” “gearbox,” and “electric motor.” There is a chain mechanism connecting all four components. The “ring gear” and “electric motor” components are composed of two independent units, one of which serves the desired purpose and the other is maintained in cold standby. The “drum” and “gearbox” of the components each contain only one unit. Therefore, a novel mathematical model is designed and implemented in this work by assuming arbitrary repair rates and exponentially distributed failure rates using the Markov process and Chapman-Kolmogorov equations. This study explored the availability with a normalization method and used genetic algorithm techniques to optimize ball mill availability. Putting this article into practice is of great benefit when developing an appropriate maintenance program. Through this, the study achieves maximum production. To investigate the behavior of several performance characteristics of the ball mill production system, numerical results and corresponding graphs are also specifically created for specific values of subsystem parameters, such as failure rate, and repair rate to increase the system’s overall efficiency.
Periungual Pyogenic Granuloma in Multiple Nails due to Isotretinoin Ahluwalia, Daisy; Bansal, Shikha; Prathibha, Kuchana; Lachyan, Abhishek
Berkala Ilmu Kesehatan Kulit dan Kelamin Vol. 36 No. 3 (2024): DECEMBER
Publisher : Faculty of Medicine, Universitas Airlangga

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20473/bikk.V36.3.2024.222-224

Abstract

Background: Isotretinoin, a first-generation nonaromatic retinoid approved in 1973 for severe nodulocystic acne treatment in the United States, has historically been associated with mucocutaneous adverse events. Case: The case involves a 22-year-old male with chronic plaque psoriasis who, after eight weeks of isotretinoin use, experienced swelling, pain, and bleeding in the periungual area of multiple fingers. Dermoscopic examination and follow-up assessments, including images, demonstrate the progression and eventual complete resolution of the periungual pyogenic granuloma following discontinuation of isotretinoin and topical application of fusidic acid and betamethasone combination. Discussion: The discussion delves into potential mechanisms linking isotretinoin to increased skin fragility and granulation tissue development, drawing on insights from experts like Baran and Piraccini. Additionally, we explore the role of angiogenic factors, particularly vascular endothelial growth factor (VEGF), in the context of psoriasis and its potential contribution to the development of pyogenic granuloma, with the aim of providing a comprehensive understanding of the underlying processes leading to this unique adverse event. Conclusion: In conclusion, this case report underscores the importance of recognizing and promptly addressing rare adverse events associated with medication errors. The successful resolution of the periungual pyogenic granuloma highlights the significance of timely intervention and appropriate management strategies in mitigating adverse outcomes.
Co-Authors Ahluwalia, Daisy Chaudhary, Priya Lachyan, Abhishek Prathibha, Kuchana