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The Analysis Study of Effectiveness and Safety of Topical Treatment for Vernal Keratoconjunctivitis: A Comprehensive Systematic Review Fazri, Karin Ananditya; Ramadhani, Fikar
The International Journal of Medical Science and Health Research Vol. 2 No. 3 (2024): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/fn3q9p69

Abstract

Background: This systematic review aims to evaluate and synthesize evidence on the efficacy and safety of topical treatments for VKC, focusing on the effectiveness of treatments like cyclosporine A, tacrolimus, and other topical therapies in alleviating symptoms and improving clinical outcomes. Methods: The review followed PRISMA 2020 guidelines, including studies published in English from 2014 to 2024. Results: Eight studies met the inclusion criteria. The review found that both cyclosporine A and tacrolimus significantly reduced symptom and sign scores in VKC patients. Rebamipide was comparable in efficacy to cyclosporine and tacrolimus. Tacrolimus showed efficacy in corticosteroid-refractory cases, while cyclosporine A reduced steroid dependency and related side effects. Conclusion: Topical cyclosporine A and tacrolimus are effective in managing VKC, with improvements in symptoms and clinical signs observed across studies. Cyclosporine A is particularly effective in reducing reliance on corticosteroids, while tacrolimus is beneficial for corticosteroid-refractory VKC. Personalized treatment strategies should be considered based on individual patient responses and tolerability.
The Analysis Study of Association of Myopia and Age-Related Cataract: A Comprehensive Systematic Review Fazri, Karin Ananditya; Ramadhani, Fikar
The International Journal of Medical Science and Health Research Vol. 2 No. 3 (2024): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/00by2s27

Abstract

Background: Cataract is a major burden for health-care providers around the world. From a public health perspective, it is important to know the prevalence of undiagnosed lens opacities. Myopia a refractive error where distant objects appear blurred due to the elongation of the eyeball is seeing a rise in prevalence worldwide, with a particular increase in Asian populations. The aim: The aim of this study to show about association of myopia and age-related cataract. Methods: By the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. This search approach, publications that came out between 2014 and 2024 were taken into account. Several different online reference sources, like Pubmed, SagePub, and Sciencedirect were used to do this. Result: Eight publications were found to be directly related to our ongoing systematic examination after a rigorous three-level screening approach. Subsequently, a comprehensive analysis of the complete text was conducted, and additional scrutiny was given to these articles. Conclusion: Low and moderate myopes are less likely to develop such a severe visual outcome; nevertheless, they are at significant risk to develop cataract.