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p-Index From 2020 - 2025
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This Author published in this journals
All Journal The International Journal of Medical Science and Health Research The Indonesian Journal of General Medicine
Prastyo, Wahyu Agus
Unknown Affiliation
Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

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The Analysis Study of  Histopathologic Diagnosis of Primary Malignant Melanoma of Esophagus : An Anatomic Pathology Comprehensive Systematic Review Prastyo, Wahyu Agus; Nugraheni, Artha Investari; Ayuningrum, Mutia Ruliana
The International Journal of Medical Science and Health Research Vol. 4 No. 4 (2024): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/a6qvsp78

Abstract

Background: Esophageal melanoma is believed to develop from melanocytes anchored in the esophageal mucosa. The aim of this study to show about histopathologic diagnosis of primary malignant melanoma of esophagus. Methods: By the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. Result: Eight publications were found to be directly related to our ongoing systematic examination after a rigorous three-level screening approach. Subsequently, a comprehensive analysis of the complete text was conducted, and additional scrutiny was given to these articles. Conclusion: A primary malignant melanoma of the esophagus (PMME) is a highly malignant tumor with a poor prognosis. A primary malignant melanoma of the esophagus (PMME) diagnosis should be made by combining clinical imaging and relying on histopathological and immunohistochemical markers. Diagnosis in the early stages and differential diagnosis, timely operation therapy, and postoperative appropriate chemotherapy and immune therapy combined with the initial patient condition may prolong survival time.
The Analysis Study of Histopathologic Diagnosis of Metastatic Basal Cell Carcinoma of Skin: A Comprehensive Systematic Review Prastyo, Wahyu Agus; Nugraheni, Artha Investari; Ayuningrum, Mutia Ruliana
The International Journal of Medical Science and Health Research Vol. 2 No. 4 (2024): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/v0ay6990

Abstract

Background: Metastatic basal cell carcinoma (MBCC) occurs at an exceedingly low rate, with an estimated incidence of 0.0028%, or 28 cases per 1,000,000 BCC diagnoses. The biological mechanisms underlying the metastatic potential of BCC remain poorly understood. This systematic review aims to evaluate the histopathologic features of MBCC based on literatures of the last 10 years. Methods: The study adhered to PRISMA 2020 standards, examining English literature from 2014 to 2024. It excluded editorials, reviews from the same journal, and submissions without a DOI. PubMed, SagePub, SpringerLink, and Google Scholar were utilized as literature sources. Result: Initially retrieving 360 articles from online databases (PubMed, SagePub, SpringerLink and Google Scholar) eight relevant papers were selected after three rounds of screening for full-text analysis. Conclusion: Histopathologic diagnosis of metastatic basal cell carcinoma is crucial for determining tumor type, assessment of invasion depth, examination of excised margins, and identification of lymphovascular or perineural invasion. Molecular analysis can reveal mutations influencing tumor behavior and treatment resistance.
The Analysis Study of Histopathologic Diagnosis of Gastroesophageal Reflux Disease: An Anatomic Pathology Comprehensive Systematic Review Prastyo, Wahyu Agus; Nugraheni, Artha Investari; Ayuningrum, Mutia Ruliana
The Indonesian Journal of General Medicine Vol. 3 No. 1 (2024): The Indonesian Journal of General Medicine
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/0n3dfp53

Abstract

Introduction : This systematic review explores the histopathologic features of GERD and its differential diagnoses, emphasizing the role of endoscopic and histologic assessments in clinical practice. Methods : A systematic review was conducted following PRISMA 2020 guidelines to evaluate the histopathologic features of GERD and its differential diagnoses. Results : From an initial pool of 6006 publications, eight studies were identified as directly relevant after a thorough screening process. The findings highlight the importance of biopsy sampling and histologic evaluation in differentiating GERD from other esophageal inflammatory conditions. Key diagnostic features included basal cell hyperplasia, elongation of lamina propria papillae, and dilatation of intercellular spaces, which were critical for distinguishing GERD from other conditions. Conclusion : This systematic review emphasizes the importance of histopathologic evaluation in the accurate diagnosis of GERD and its differential diagnoses. Understanding the distinct histopathologic features of GERD, as well as technical aspects of biopsy sampling, is essential for improving diagnostic accuracy and preventing progression to severe complications.
Co-Authors Ayuningrum, Mutia Ruliana Nugraheni, Artha Investari