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The Analysis Study of Diagnosis and Management of Respiratory Distress Syndrome in Neonatus: A Comprehensive Systematic Review Aldila, Raden Rara Farah; Erlich, Willyam Arnando Deggas
The International Journal of Medical Science and Health Research Vol. 4 No. 4 (2024): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/v9vzhr68

Abstract

Background: Respiratory distress syndrome (RDS) management is crucial for preterm infants, as it aims to improve survival rates while minimizing the risk of adverse outcomes, particularly bronchopulmonary dysplasia (BPD). Methods: This systematic review exclusively examined full-text articles published in English between 2014 and 2024, adhering to the PRISMA 2020 guidelines. Result: The study conducted a thorough review of more than 4000 publications that were obtained from reputable databases, such as ScienceDirect, SagePub, and PubMed. Eight publications were identified as necessitating a more comprehensive examination subsequent to an initial screening. As a result, a comprehensive review of these selected studies was conducted to guarantee an exhaustive and rigorous assessment. Conclusion: RDS diagnosis and management differ significantly between Japan and Europe, with neonatologists administering surfactants based on confirmed diagnosis rather than FiO2 levels. In Japan, chest radiography and stable microbubble rating are commonly used diagnostic tools, but accuracy can be influenced by variability and sample contamination. Challenges remain in distinguishing RDS from transient tachypnea.
The Analysis Study of Early Detection and Outcome of Speech Delay in Children: A Comprehensive Systematic Review Aldila, Raden Rara Farah; Erlich, Willyam Arnando Deggas
The International Journal of Medical Science and Health Research Vol. 4 No. 5 (2024): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/hpaavy19

Abstract

Background: Children of school age with language or speech delays are at a higher risk of encountering learning and literacy difficulties, particularly in reading and writing. This systematic review aims to evaluate the early detection and outcome of speech delay in children based on the literatures of the last 10 years. Methods: The study adhered to PRISMA 2020 standards, examining English literature from 2014 to 2024. It excluded editorials, reviews from the same journal, and submissions without a DOI. PubMed, SagePub, SpringerLink, and Google Scholar were utilized as literature sources. Result: Initially retrieving 360 articles from online databases (PubMed, SagePub, SpringerLink and Google Scholar) eight relevant papers were selected after three rounds of screening for full-text analysis. Conclusion: Speech delay affects children's language and literacy, highlighting the need for early detection and intervention. Tailored diagnostic tools and understanding contributing factors are essential for implementing effective screening and targeted interventions to improve outcomes and foster positive developmental trajectories
The Analysis Study of Effects of Probiotics, Prebiotics, Lactoferrin and Combination Products for Prevention of Mortality and Morbidity in Preterm Infants: A Comprehensive Systematic Review Aldila, Raden Rara Farah; Erlich, Willyam Arnando Deggas
The Indonesian Journal of General Medicine Vol. 4 No. 1 (2024): The Indonesian Journal of General Medicine
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/xt75hd29

Abstract

Introduction: Preterm infants, particularly those with very low birth weight (VLBW), are at heightened risk for life-threatening complications such as necrotizing enterocolitis (NEC), late-onset sepsis, feeding intolerance, and other gastrointestinal and infectious conditions. In recent years, there has been growing interest in exploring non-pharmacological interventions, such as probiotics, prebiotics, and lactoferrin, to mitigate these risks and improve outcomes in preterm infants. Methods: This systematic review adhered to the PRISMA 2020 guidelines to ensure transparency and consistency. Results: Eight relevant studies were identified and assessed in detail. Findings indicate that probiotic, prebiotic, and lactoferrin interventions have potential benefits in reducing NEC incidence and improving clinical outcomes in VLBW infants. For instance, a study by Chowdhury et al. (2016) found a significantly lower incidence of NEC in the probiotic group (1.9%) compared to the control group (11.5%) with a p-value of 0.044. Additionally, the duration of hospital stay was shorter for the probiotic group, averaging 15.82 days versus 19.57 days for controls (p < 0.001). These results support the use of probiotics in enhancing recovery in VLBW infants. This review highlights the potential of probiotics, prebiotics, and lactoferrin in reducing the incidence of NEC and sepsis, as well as promoting faster achievement of full enteral feeding and shorter hospital stays in VLBW infants. However, the heterogeneity among studies regarding probiotic strains, dosages, and study designs complicates definitive conclusions. Further research is needed to establish standardized treatment protocols and ensure the long-term safety of these interventions in clinical practice.