Article Per Year (5 Year)
p-Index From 2021 - 2026
0.444
P-Index
This Author published in this journals
All Journal Academia Open Indonesian Journal Health Science and Medicine
Eneama, Wijdan Abbas
Unknown Affiliation
Agriculture, Biological Sciences & Forestry Arts Humanities Chemistry Computer Science & IT Earth & Planetary Sciences Economics, Econometrics & Finance Environmental Science Health Professions Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Library & Information Science Medicine & Pharmacology Physics Public Health Social Sciences Veterinary Other

Published : 2 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 2 Documents
Search

 1 
Isoxazolidine Derivatives Exhibit Selective Antitumor Activity Against Breast Cancer Cells Eneama, Wijdan Abbas; Salman, Husam Hamza; Mousa , Mazin N`adhim
Academia Open Vol 9 No 2 (2024): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.9.2024.8148

Abstract

Breast cancer, a leading cause of cancer-related mortality in women, necessitates effective therapeutic interventions. Heterocyclic compounds, prevalent in FDA-approved pharmaceuticals, play a pivotal role in drug development. This study focuses on isoxazolidine derivatives, a subgroup of nitrogen and oxygen-containing heterocycles, known for their potential in antitumor applications. A series of novel isoxazolidine compounds were synthesized and evaluated for their anticancer efficacy using MTT assays against MCF-7 and HdFn cell lines, alongside normal cells. Structural elucidation employed FT-IR, 13C-NMR, 1H-NMR, and E-I mass spectroscopy. Results revealed compound (IZ3) with an IC50 value of 32.49 µg/ml, demonstrating notable antitumor activity in MCF-7 cells compared to HdFn. Notably, compounds (IZ1 and IZ2) exhibited IC50 values of 64 µg/ml and 128 µg/ml, respectively. These findings underscore the potential of isoxazolidine derivatives as promising candidates for targeted breast cancer therapies, warranting further investigation in preclinical models and clinical trials. Highlight: Novel Isoxazolidine Compounds: Synthesized and Evaluated Selective Antitumor Activity: Demonstrated in MCF-7 Breast Cancer Cells Promising Therapeutic Candidates: Isoxazolidine Derivatives for Targeted Breast Cancer Therapy Keyword: Breast cancer, Isoxazolidine Derivatives, Antitumor Activity, Heterocyclic Compounds, Drug Development
Syncope and Hip Fracture Incidence Among the Elderly: Insiden Pingsan dan Patah Tulang Pinggul pada Lansia Eneama, Wijdan Abbas; Naser , Rand Salah; Issa, Wafaa Abdulkadhim
Indonesian Journal on Health Science and Medicine Vol. 2 No. 2 (2025): Oktober
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v2i2.212

Abstract

General Background: Syncope, a transient loss of consciousness due to reduced cerebral blood flow, is a common geriatric condition linked to falls and injury. Specific Background: In older adults, the combination of comorbidities, impaired balance, and bone fragility increases susceptibility to severe consequences such as hip fractures, which are associated with high morbidity and mortality. Knowledge Gap: While syncope is recognized as a fall risk factor, its direct relationship with hip fracture prevalence and fracture severity patterns in elderly populations remains underexplored. Aims: This study aimed to quantify hip fracture incidence among elderly patients with syncope, identify high-risk subgroups, and assess the influence of syncope characteristics on fracture severity. Results: In a cross-sectional study of 200 patients, 36% sustained fractures, including 16% hip fractures; prolonged syncope (>2 minutes), absence of warning signs, and recurrent episodes were strongly associated with severe injuries. Women aged 45–50 with balance disorders or chronic conditions were disproportionately affected. Novelty: The research delineates a duration–severity gradient for syncope-induced fractures and highlights modifiable clinical predictors. Implications: Targeted preventive strategies—such as syncope workups, balance rehabilitation, and bone health screening—may substantially reduce fracture-related disability and mortality in at-risk elderly populations.Highlight : Syncope is a major risk factor for injury in older adults. Hip fractures were found in 16% of syncope patients. The duration of syncope affects the severity of fractures. Keywords : Syncope In Elderly, Hip Fractures, Falls Related Injuries, Fracture Patterns, Risk Factors
Co-Authors Issa, Wafaa Abdulkadhim Mousa , Mazin N`adhim Naser , Rand Salah Salman, Husam Hamza