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Khalaf, Qasim Ibrahim
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Toxoplasma Infection Alters Lipid Profiles Challenging Cardiovascular Norms Khalaf, Qasim Ibrahim
Academia Open Vol 9 No 2 (2024): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.9.2024.9103

Abstract

This study conducted at Baquba Teaching Hospital from January to April 2024, investigated the lipid profiles of 75 participants (50 patients with Toxoplasma and 25 controls) aged between 50 and 60 years. Existing research suggests a potential link between Toxoplasma infection and alterations in lipid metabolism; however, specific effects on different lipid fractions are not well-understood. This study aimed to explore the association between Toxoplasma infection and changes in lipid profiles, particularly focusing on whether infection status correlates with variations in high-density lipoprotein (HDL) levels. Venous blood samples were collected pre-breakfast and processed to obtain serum, which was analyzed for lipid profiles. The findings indicated that lipid levels generally increased in Toxoplasma patients compared to controls, except for a decrease in HDL levels. These results suggest that Toxoplasma infection could influence lipid metabolism, potentially impacting cardiovascular risk. Further research is needed to understand the mechanisms underlying these changes and their clinical implications. Highlights: Toxoplasma infection is linked to significant changes in lipid profiles. The study identifies a unique decrease in HDL levels among infected individuals. Implications suggest potential cardiovascular risks associated with Toxoplasma. Keywords: Toxoplasma, Lipid Metabolism, Cardiovascular Risk, HDL Decrease
Gender Age Disparity in Amoebiasis Prevalence in Iraq Khalaf, Qasim Ibrahim
Academia Open Vol 9 No 2 (2024): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.9.2024.9104

Abstract

This comparative cross-sectional study evaluates the prevalence of Entamoeba histolytica, the causative agent of amoebiasis, in the human population of Diyala Governorate, conducted at Alshams Medical Labs in Baqubah city. Despite the global health burden of amoebiasis, particularly in developing countries, data on its age and gender-specific prevalence remain sparse. Aimed at filling this knowledge gap, our research specifically assessed the distribution of E. histolytica in males and females across two age groups (1-15 years and 15-45 years). The study found that 74% of females aged 1-15 years harbored both cysts and trophozoites, while males of the same age group showed a markedly lower prevalence at 19%. In the 15-45 year age group, males demonstrated a higher prevalence (50%) compared to females (9%). These findings suggest significant gender and age-related disparities in the prevalence of E. histolytica. The results could inform targeted public health interventions and contribute to more effective management and prevention strategies for amoebiasis in endemic regions. Highlights: Gender Disparity: Marked differences in infection rates between males and females. Age Influence: Varied prevalence across different age groups. Health Strategy Needs: Highlights the necessity for targeted public health interventions. Keywords: Amoebiasis, Entamoeba Histolytica, Prevalence, Gender Disparity
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