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Association between Relative Risk Factor (RR) and ABO Blood Groups with Clinical Parameters in Patients with SARS-Cov-2 Yousif, Abdullah Fakhir; Mahdi, Abeer Ghassan
Academia Open Vol 9 No 2 (2024): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.9.2024.9156

Abstract

This study investigates the correlation between ABO blood groups and SARS-CoV-2 infection among 1,303 participants from Babylon, comprising 397 infected individuals and 906 healthy controls. It explores three primary axes: genetic inheritance of ABO blood groups in 200 families, distribution of these blood groups in the context of SARS-CoV-2 infection, and the relationship of these blood groups with various physiological indicators in infected, recovered, and healthy subjects. The findings reveal that the AB blood group is disproportionately associated with a higher infection rate (RR = 1.808), whereas the O group shows a lesser susceptibility (RR = 0.901). Additionally, physiological changes such as decreased lymphocytes, MCH, and MCHC, alongside increased WBC, CRP, Ferritin, D-dimer, and LDH levels were noted in infected individuals. This study underscores the potential of ABO blood groups as a factor in COVID-19 infection risk, suggesting a direction for future research into tailored medical responses based on genetic predispositions. Highlights: Blood Group Impact: AB group had higher COVID-19 infection rates; O group had lower. Physiological Indicators: Infected individuals showed significant changes in key blood parameters. Medical Strategy: Findings suggest potential for personalized medical approaches based on ABO blood groups. Keywords: SARS-Cov-2, ABO Blood Groups, Relative Risk Factor
Estimation the Correlation between Heavy Metals and Oxidative Stress in People Living Near Incineration in Al-Nasr City in Thi-qar Governorate: Estimasi Korelasi antara Logam Berat dan Stres Oksidatif pada Orang yang Tinggal di Dekat Insinerasi di Kota Al-Nasr di Kegubernuran Thi-qar Yousif, Abdullah Fakhir
Indonesian Journal on Health Science and Medicine Vol. 1 No. 2 (2024): October
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v1i2.41

Abstract

Abstract. Background: The current study is a prospective research. Some laboratory tests were done on people living near incineration in Al-Nasr city in thi-qar governorate. This scientific study has its goal as providing social benefits through supporting and augmenting the efforts of Environmental Authority in their work of organizing and monitoring waste disposal processes, with due consideration to the health status of these individuals to help decrease the incidence of waste burning besides finding safe solutions for waste disposal. Methods: The samples were collected from people living near incineration in Al-Nasr city in Thi-Qar governorate. Seventy five samples of blood obtained from subjects residing near incineration, and seventy five samples also obtained from normal individuals as a control group, subject's age ranged between (20-60) years, during the period from October 2022 up to April 2023. Serum levels were assayed for lead (Pb), cadmium (Cd), zinc (Zn), malondialdehyde (MDA), Glutathione (GSH) and albumin (Alb). Results: A highly significant increase in serum Pb, serum Cd, serum Zn, and serum MDA in people living near incineration as compared to the control group was observed. A significant decrease in serum GSH, and serum Alb in people living near incineration as compared to the controls group was found. The study reported a positive correlation between Pb and (Cd, Zn, MDA) while it reported a negative correlation between Pb and (GSH, Alb). Highlights: Prospective study on health impacts of incineration in Al-Nasr city. Blood tests on 75 residents, 75 controls; analyzed Pb, Cd, Zn, MDA, GSH, Alb. Increased Pb, Cd, Zn, MDA; decreased GSH, Alb; correlations observed. Keywords: Oxidative stress, Lead, Cadmium, Zinc, Glutathione, Albumin