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Fejer, Lamyaa Gh.
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Honey Enhances Antibiotic Effectiveness Against Urinary Tract Infections Fejer, Lamyaa Gh.; Hameed, Ghaidaa S.; Ali, Mayssam Hussein Mohammed; Al-Hammood, Orooba
Academia Open Vol 9 No 2 (2024): December
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/acopen.9.2024.9870

Abstract

Background: Urinary tract infections (UTIs) are prevalent across all ages and genders and pose significant treatment challenges, often requiring alternative therapeutic approaches due to increasing antibiotic resistance. Specific Background: The study examines the impact of antibiotics and honey on bacterial UTIs, revealing 17 cases, primarily caused by Staphylococcus aureus and Klebsiella pneumoniae. Knowledge Gap: The study evaluates the effectiveness of honey in combining antibiotics with anise and spring flower honey, focusing on its potential to enhance antimicrobial effects in UTIs. Results: Biochemical analysis and VITEK diagnostics revealed significant bacterial growth. Antibiotic susceptibility tests showed varied effectiveness, with spring flower honey enhancing the activity of nitrofurantoin (35%), trimethoprim (17.6%), trimethoprim-sulfamethoxazole (23.5%), tetracycline, and norfloxacin (35.2%). Anise honey also demonstrated notable synergistic effects, particularly with norfloxacin (47%) and tetracycline (41%). Novelty: This study highlights the potential of combining honey with antibiotics to combat UTIs, offering new insights into alternative treatment strategies and demonstrating significant synergy with specific antibiotics. Implications: The findings suggest that incorporating honey into UTI treatments could improve therapeutic outcomes and help mitigate the growing issue of antibiotic resistance. Further research is needed to identify active compounds in honey and optimize their use with antibiotics. Highlights: Enhanced Efficacy: Honey boosts antibiotic effectiveness against UTIs. Resistance Solution: Combines honey to counteract antibiotic resistance. Honey Variability: Different honeys show varied synergistic effects. Keywords: Urinary Tract Infection, Antibiotics, Honey, Synergistic Effect, Antibiotic Resistance
Comparison Study of Diaspot Rapid One Test and Advanced Quality Test in the Diagnosis of H. Pylori from Smokers Fejer, Lamyaa Gh.
Indonesian Journal on Health Science and Medicine Vol. 2 No. 1 (2025): July
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/ijhsm.v2i1.185

Abstract

Background :Helicobacter pylori is a microaerophilic, gram-negative bacterium that colonizes the human gastrointestinal tract and represents one of the most widespread bacterial infections globally. Several studies have shown a strong correlation between smoking and increased susceptibility to H. pylori infection, with smokers demonstrating a higher infection rate compared to non-smokers.Aims:This study aims to determine the most accurate and reliable diagnostic method for detecting H. pylori among smokers. Method:A comparative analysis was conducted between two rapid diagnostic tools: the Diaspot Rapid One Test and the Advanced Quality Rapid Anti-H. pylori Test. Both tests were applied to blood and stool samples collected from 100 male and female smokers at Al-Mustafa University College over a five-month period (September 2019–February 2020).Findings:Results revealed that 10% of the blood samples tested positive, whereas all stool samples returned negative results.Results:These findings suggest that stool testing may offer more accurate detection, as blood antibodies can persist even after the infection has resolved, potentially causing false positives. The study highlights the limitations of relying on a single diagnostic method, especially in smokers, and recommends the adoption of multimodal diagnostic approaches to enhance accuracy in high-risk populations. Highlights: Stool tests may be more accurate for current infections. Blood antibodies can cause false positives. Smokers are at higher risk for H. pylori infection. Keywords: Helicobacter Pylori, Smokers, Rapid Diagnostic Test, Stool Testing, Blood Antibody
Co-Authors Al-Hammood, Orooba Ali, Mayssam Hussein Mohammed Hameed, Ghaidaa S.