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THE PATHOPHYSIOLOGY OF ULCERATIVE COLITIS. THE CURRENT STATE OF THE PROBLEM OF ETIOLOGY, EARLY DIAGNOSIS AND TREATMENT Bakhodirovna, Salimova Nigora
Journal of Contemporary Business Law & Technology: Cyber Law, Blockchain, and Legal Innovations Vol. 1 No. 8 (2024): Journal of Contemporary Business Law & Technology: Cyber Law, Blockchain, and L
Publisher : PT ANTIS International Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/ejcblt.v1i8.946

Abstract

General Background: Ulcerative colitis (UC) and Crohn's disease (CD) are chronic inflammatory bowel diseases that significantly impact patients' quality of life and present substantial healthcare challenges globally. Specific Background: This review provides a comprehensive analysis of contemporary literature regarding the etiology, pathophysiology, diagnosis, and treatment of UC and CD. It highlights the prevalence of these conditions both worldwide and specifically in Uzbekistan, emphasizing their clinical significance. Knowledge Gap: Despite advancements in understanding these diseases, challenges persist in the early diagnosis and management of UC and CD, particularly due to the absence of standardized diagnostic tests for assessing intestinal inflammation. Aims: The objective of this review is to synthesize current knowledge on the interplay between UC and primary sclerosing cholangitis, explore therapeutic options available internationally, and identify effective pharmacological agents used to achieve and maintain remission. Results: The findings reveal critical insights into the epidemiological trends of UC and CD, the complex relationship between these diseases and primary sclerosing cholangitis, and the varied therapeutic strategies employed in different countries. Novelty: This review uniquely addresses the underexplored relationship between UC and primary sclerosing cholangitis while providing a focused discussion on therapeutic modalities that may enhance patient outcomes. Implications: The insights gained from this analysis underscore the need for improved diagnostic methods and tailored treatment approaches to better manage UC and CD, ultimately informing clinical practice and guiding future research in this area.
CLINICAL AND PATHOGENETIC CHARACTERISTICS OF PEPTIC ULCER OF THE STOMACH AND DUODENUM Bakhodirovna, Salimova Nigora
Journal of Artificial Intelligence and Digital Economy Vol. 1 No. 9 (2024): Journal of Artificial Intelligence and Digital Economy
Publisher : PT ANTIS INTERNATIONAL PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jaide.v1i9.943

Abstract

In order to assess the clinical, pathogenetic, functional variant of the course of peptic ulcer disease, I conducted a study of 112 patients with gastric ulcer (34), duodenal ulcer (78). The diagnosis was verified in accordance with the requirements of the modern standard, with an assessment of histomorphological secretory motor, hormonal disorders, as well as the degree of N. rulori contamination, eradication and its effectiveness. Psychosomatic status was assessed using complex methods: multilateral personality studies, the Hamilton scale for assessing depression, the Spielberg scale of situational and personal anxiety, the Beck depression scale, the "unfinished sentences" method for assessing violations in the relationship system.
THE PATHOPHYSIOLOGY OF ULCERATIVE COLITIS. THE CURRENT STATE OF THE PROBLEM OF ETIOLOGY, EARLY DIAGNOSIS AND TREATMENT Bakhodirovna, Salimova Nigora
Journal of Contemporary Business Law & Technology: Cyber Law, Blockchain, and Legal Innovations Vol. 1 No. 8 (2024): Journal of Contemporary Business Law & Technology: Cyber Law, Blockchain, and L
Publisher : Antis Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/ejcblt.v1i8.946

Abstract

General Background: Ulcerative colitis (UC) and Crohn's disease (CD) are chronic inflammatory bowel diseases that significantly impact patients' quality of life and present substantial healthcare challenges globally. Specific Background: This review provides a comprehensive analysis of contemporary literature regarding the etiology, pathophysiology, diagnosis, and treatment of UC and CD. It highlights the prevalence of these conditions both worldwide and specifically in Uzbekistan, emphasizing their clinical significance. Knowledge Gap: Despite advancements in understanding these diseases, challenges persist in the early diagnosis and management of UC and CD, particularly due to the absence of standardized diagnostic tests for assessing intestinal inflammation. Aims: The objective of this review is to synthesize current knowledge on the interplay between UC and primary sclerosing cholangitis, explore therapeutic options available internationally, and identify effective pharmacological agents used to achieve and maintain remission. Results: The findings reveal critical insights into the epidemiological trends of UC and CD, the complex relationship between these diseases and primary sclerosing cholangitis, and the varied therapeutic strategies employed in different countries. Novelty: This review uniquely addresses the underexplored relationship between UC and primary sclerosing cholangitis while providing a focused discussion on therapeutic modalities that may enhance patient outcomes. Implications: The insights gained from this analysis underscore the need for improved diagnostic methods and tailored treatment approaches to better manage UC and CD, ultimately informing clinical practice and guiding future research in this area.