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All Journal JMGCB Journal of Medical Genetics and Clinical Biology (JMGCB)
Radhi, Zahraa Essa
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience Nursing

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PREPARING NANOPARTICLES USING SOME BIOLOGICAL METHODS AND STUDYING THEIR EFFECT ON SOME MYCOTOXINS Radhi, Zahraa Essa; Azeez, Zahraa Falah
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 9 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT ANTIS INTERNATIONAL PUBLISHER

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i9.944

Abstract

General Background: Mycotoxins, toxic substances produced by certain fungi and bacteria, pose significant health risks to humans and animals, necessitating effective remediation strategies. Specific Background: The use of environmentally friendly approaches to mitigate the impact of these toxins is crucial. Nanotechnology, particularly in conjunction with plant extracts, has emerged as a promising method for toxin remediation due to its cost-effectiveness and efficiency. Knowledge Gap: Despite the potential of nanomaterials in mycotoxin management, there is limited research exploring the interaction between plant extracts and nanotechnology in inhibiting toxin-producing fungi. Aims: This study aims to investigate the efficacy of zinc oxide nanomaterials synthesized from mint plant extracts in mitigating the effects of mycotoxins and inhibiting the growth of mycotoxin-producing fungi. Results: Mint leaves were collected from various locations in Al-Qadisiyah Governorate over an eight-week period. The extracted plant materials were used to synthesize zinc oxide nanoparticles, which demonstrated significant inhibitory effects on the growth of specific fungi responsible for mycotoxin production, thereby reducing mycotoxin formation. Novelty: This research highlights the innovative application of mint-derived zinc oxide nanoparticles as a dual-action agent—suppressing fungal growth while simultaneously preventing mycotoxin synthesis. Implications: The findings provide valuable insights into sustainable agricultural practices and mycotoxin management, paving the way for the development of natural, eco-friendly solutions to enhance food safety and protect public health.
PREPARING NANOPARTICLES USING SOME BIOLOGICAL METHODS AND STUDYING THEIR EFFECT ON SOME MYCOTOXINS Radhi, Zahraa Essa; Azeez, Zahraa Falah
Journal of Medical Genetics and Clinical Biology Vol. 1 No. 9 (2024): Journal of Medical Genetics and Clinical Biology
Publisher : PT. Antis International Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v1i9.944

Abstract

General Background: Mycotoxins, toxic substances produced by certain fungi and bacteria, pose significant health risks to humans and animals, necessitating effective remediation strategies. Specific Background: The use of environmentally friendly approaches to mitigate the impact of these toxins is crucial. Nanotechnology, particularly in conjunction with plant extracts, has emerged as a promising method for toxin remediation due to its cost-effectiveness and efficiency. Knowledge Gap: Despite the potential of nanomaterials in mycotoxin management, there is limited research exploring the interaction between plant extracts and nanotechnology in inhibiting toxin-producing fungi. Aims: This study aims to investigate the efficacy of zinc oxide nanomaterials synthesized from mint plant extracts in mitigating the effects of mycotoxins and inhibiting the growth of mycotoxin-producing fungi. Results: Mint leaves were collected from various locations in Al-Qadisiyah Governorate over an eight-week period. The extracted plant materials were used to synthesize zinc oxide nanoparticles, which demonstrated significant inhibitory effects on the growth of specific fungi responsible for mycotoxin production, thereby reducing mycotoxin formation. Novelty: This research highlights the innovative application of mint-derived zinc oxide nanoparticles as a dual-action agent—suppressing fungal growth while simultaneously preventing mycotoxin synthesis. Implications: The findings provide valuable insights into sustainable agricultural practices and mycotoxin management, paving the way for the development of natural, eco-friendly solutions to enhance food safety and protect public health.
THE EFFECT OF MICROBES ISOLATED FROM THE FEMALE REPRODUCTIVE TRACT OF PREGNANT WOMEN ON FETUSES Radhi, Zahraa Essa; Al-Saadi, Dania Ali Azeiz; Alhachem, Hind Fieq Abdalameer; Al-Khafaji , Zainab Abdul Jabbar; Harjan, Qusay Jabbar
Journal of Medical Genetics and Clinical Biology Vol. 2 No. 7 (2025): Journal of Medical Genetics and Clinical Biology
Publisher : PT. Antis International Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.61796/jmgcb.v2i7.1368

Abstract

Objective: This study explores the role of microorganisms isolated from the female reproductive tract during pregnancy and their potential impact on fetal development and pregnancy complications. Method: A descriptive, literature-based approach was employed to analyze microbial populations across various anatomical sites—vaginal, cervical, endometrial, tubal, and ovarian—focusing on their interactions with the maternal immune system and reproductive outcomes. Results: The findings reveal that microbial imbalance, particularly the reduction of Lactobacillus species, disrupts immune regulation and compromises epithelial integrity, leading to adverse outcomes such as premature labor, miscarriage, infections, and congenital abnormalities. Pathogens including Candida, Trichomonas, Cytomegalovirus, and Group B Streptococcus were identified as major contributors to these complications. Novelty: Unlike prior studies that often examine isolated reproductive sites, this research integrates microbiome data from both upper and lower reproductive tracts, offering a comprehensive view of organ-specific dysbiosis and its influence on maternal-fetal health. These insights suggest new directions for preventive strategies, targeted therapies, and the development of biomarkers aimed at restoring microbial equilibrium to safeguard pregnancy outcomes.
Co-Authors Al-Khafaji , Zainab Abdul Jabbar Al-Saadi, Dania Ali Azeiz Alhachem, Hind Fieq Abdalameer Azeez, Zahraa Falah Harjan, Qusay Jabbar