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All Journal Saintika Medika: Jurnal Ilmu Kesehatan dan Kedokteran Keluarga. Farmasains : Jurnal Farmasi dan Ilmu Kesehatan
Miftha Churochman
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Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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A Comprehensive Review of the Current Understanding and Future Directions in Biofilms and Antibiotic Resistance in Chronic Rhinosinusitis Indra Setiawan; Miftha Churochman
Farmasains : Jurnal Farmasi dan Ilmu Kesehatan Vol. 8 No. 1 (2023)
Publisher : Universitas Muhammadiyah Malang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22219/farmasains.v8i1.33659

Abstract

This paper aims to analyze and evaluate the impact of social media on society. The study examines about Chronic Rhinosinusitis (CRS) that is the multifactorial inflammatory disease of the nasal and paranasal mucosae for more than 12 weeks. Chronic Rhinosinusitis (CRS) is a highly widespread condition that has a significant impact on a large population around the globe. There has been a notable increase in the focus on the significance of biofilms and antibiotic resistance in the pathophysiology of chronic rhinosinusitis (CRS). The objective of this review is to consolidate existing scholarly literature on the aforementioned subjects, drawing from a selection of five prominent peer-reviewed works, while also suggesting potential avenues for further research. The objective of this study is to consolidate existing information regarding the involvement of biofilms and antibiotic resistance in the etiology and treatment of Chronic Rhinosinusitis (CRS), and to suggest potential avenues for future research. The study utilized a qualitative research methodology, integrating data from five primary scholarly papers that centered on topics such as chronic rhinosinusitis (CRS), biofilms, antibiotic resistance, and therapeutic approaches. The process involved the extraction and analysis of data in order to discover prevalent themes, inconsistencies, and areas of research that have not been adequately addressed in the current body of literature. In conclusion, it can be inferred that the given information supports the notion that biofilms have been found to have a substantial impact on the pathophysiology of chronic rhinosinusitis (CRS), leading to increased disease severity and posing difficulties in its management. Gaining comprehension of the underlying mechanisms involved in the process of biofilm formation and the development of antibiotic resistance might provide valuable diagnostic and therapeutic perspectives. Subsequent investigations ought to prioritize the advancement of therapeutic interventions targeting biofilm formation and the acquisition of a more comprehensive comprehension of the microbiome in chronic rhinosinusitis (CRS).
Epidemiology of Data: Critical Analysis of Under-Reporting the Double Burden of Nutrition and Its Comorbidities in Pediatric Patients Imanullah Akbar Izza Patria; Rinawati; Thontowi Djauhari Nur Subchi; Miftha Churochman
Saintika Medika : Jurnal Ilmu Kesehatan dan Kedokteran Keluarga Vol. 21 No. 2 (2025): December 2025
Publisher : Universitas Muhammadiyah Malang

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Abstract

Background: The Double Burden of Nutrition (DBGH) is a public health issue in urban areas of Indonesia. Hospitals are in a unique position to assess the clinical effects of DBGH. However, there are strong suspicions that medical records in hospitals significantly underreport this information. This situation hides the full extent of the problem, which then hinders the proper allocation of resourcesObjectives: T(1) to describe the epidemiological features of pediatric patients with DBGH (Malnutrition/E40-E46 and Obesity/E66) at Muhammadiyah General Hospital Malang (RSUMM) from 2019 to 2025, including diagnosed prevalence, age distribution, and sex; (2) to critically evaluate the diagnosed prevalence (N=1,092) by comparing it to community prevalence, considering the possibility of under-reporting; and (3) to analyze the patterns of comorbidities in the cases that were successfully recorded.Methods: This study used a quantitative, descriptive epidemiological design, specifically a cross-sectional approach. Data were gathered from the electronic medical records of pediatric patients, aged 0-18 years, who had been diagnosed with malnutrition (ICD-10 codes E40-E46) or obesity (E66) at RSUMM between January 1, 2019, and December 31, 2025. This process yielded a total sample size (N) of 1,092 cases.Results During the study, we found 1,092 cases of BGG in the medical records. Of the total, 671 cases (61.4%) were classified as Malnutrition (E40-E46), while 421 cases (38.6%) were classified as Obesity (E66). The highest rate of diagnosed cases was found in the 0-5 age group, which had a rate of 65.9%. Although the 1,092 cases seem substantial and are increasing, a critical examination reveals that this number is considerably lower than estimates of the community-level burden of BGG (e.g., national stunting prevalence in 2023 SKI >20%), suggesting considerable under-reporting. Analysis of the data shows a significant increase in BGG cases, going from 100 cases in 2019 to 250 cases by 2024. Acute Respiratory Infections (ARI/Pneumonia) and Diarrhea (Gastroenteritis) are the most common health problems seen with BGG.
Co-Authors Imanullah Akbar Izza Patria Indra Setiawan Rinawati Thontowi Djauhari Nur Subchi