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Akbari, Atika

Department Of Child Health, Sriwijaya University Medical School/Dr. Mohammad Hoesin Hospital, Palembang, South Sumatera

Author-ID : 778837

Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Environmental Science Health Professions Materials Science & Nanotechnology Medicine & Pharmacology Nursing Physics Public Health

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ASSOCIATION BETWEEN SERUM ALBUMIN LEVELS WITH THE PERCENTAGE AND LOCATION OF EDEMA IN CHILDREN WITH NEPHROTIC SYNDROME AT RSUP DR. MOHAMMAD HOESIN PALEMBANG 2016-2017 Ainun Mardiyyah; Hertanti Indah Lestari; Atika Akbari
Majalah Kedokteran Sriwijaya Vol 51, No 1 (2019): Majalah Kedokteran Sriwijaya
Publisher : Fakultas Kedokteran Universitas Sriwijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36706/mks.v51i1.8547

Edema merupakan gejala klinis utama pada anak penderita sindrom nefrotik (SN).Edema pada SN terbagi menjadi edema lokal dan anasarka yang dapat dijelaskan dengan teori underfill dimana hipoalbuminemia merupakan faktor kunci terjadinya edema. Selama ini persentase edema anak penderita SN hanya perkiraan, sedangkan berat badan kering anak penderita SN diperlukan untuk menghitung dosis kortikosteroid secara tepat. Penelitian ini bertujuan untuk mengetahui hubungan antara kadar albumin serum dengan persentase dan lokasi edema pada anak penderita sindrom nefrotik di RSUP Dr. Mohammad Hoesin Palembang periode 2016-2017. Penelitian ini merupakan penelitian observasional analitik dengan pendekatan cross sectional menggunakan data sekunder. Sampel diambil dengan menggunakan metode consecutive sampling dari seluruh data rekam medik pasien anak penderita SN di RSUP Dr. Mohammad Hoesin Palembang. Subjek terdiri dari 26 (56,5%) anak laki-laki dan 20 (43,5%) anak perempuan dengan usia rata-rata 7 tahun 2 bulan. Klasifikasisindrom nefrotik yang paling banyak ditemui adalah sindrom nefrotik inisial yang berjumlah 15 orang (32,6%). Rata-rata kadar albumin terendah dapat ditemui pada kelompok usia 4-6 tahun (1,55 g/dL) sedangkan tertinggi pada kelompok usia 13-15 tahun (2,06 g/dL). Rata-rata persentase edema tertinggi terdapat pada kelompok usia 1-3 tahun (17,38%) sedangkan terendah pada kelompok usia 16-17 tahun (3,98%). Pasien yang mengalami edema anasarka (56,5%) lebih banyak dibandingkan dengan edema lokal (43,5%). Analisis korelasi Spearman menunjukkan hubungan yang sangat bermakna (p=0,003) dengan kekuatan sedang (r=-0,424) antara kadar albumin serum dan persentase edema. Analisis Mann-Whitney (p=0,048) menunjukkan terdapat hubungan antara kadar albumin serum dan lokasi edema. Terdapat korelasi yang bermakna antara kadar albumin serum dan persentase edema. Terdapat hubungan yang bermakna antara kadar albumin serum dan lokasi edema.

Correlation Among Education, Knowledge, And Economics Of Mother Toward Antipyretic Drug Usage For Toddler In Kangkung Village OKUT Sumsel 2017 Rennie Puspa Novita; Atika Akbari; Nikita Surya Dharma; Endang Putria Sukma
Science and Technology Indonesia Vol. 3 No. 2 (2018): April
Publisher : Research Center of Inorganic Materials and Coordination Complexes, FMIPA Universitas Sriwijaya

Fever is a symptom mostly happen with all diseases which condition shows elevated body temperature above normal (38°C) that are common among toddler. Handling fever using antipyretics should be considered related to the rationale of its use. Rationality aspect which include indication accuracy, precision of medicine, patient accuracy, dosage accuracy and precision of administration, and as well as alert to side effects. Handling fever in toddlers is very dependent on the role of parents especially mother. Different maternal education, knowledge, and economics will result in the rationale of the use of different antipyretic drugs. This study aimed to investigate whether there is relation among education, knowledge, and economics of mother toward antipyretic drug usage for toddler in Kangkung Village OKUT SUMSEL 2017 by using cross sectional design. The sample was collected using simple random sampling to get 47 samples which fulfilled the inclusion criteria. The data were collected by interview based on questionnaire and analyzed by Chi-Square test using SPSS® version 23.0. The data presented descriptively showed most of the respondents were highly educated (66%), high knowledge (61.7%), and low economic level (93.6%) and the rational use of antipyretic for toddler were 100% for appropriate drug indication, precision of medicine, patient appropriateness, and alert for side effects, as well as 31.9% dosage precision and mode of administration. The result of Chi-Square test showed that the p value for education level (p >0.05) and economic level (p >0.05) had no significant correlation, meanwhile the knowledge level (p <0.05) showed significant different to the rational use of antipyretic for toddler. It can be concluded that the knowledge toward of mother affect the rational use of antipyretic for toddler in Kangkung village OKUT regency SUMSEL 2017.

Scoring system to distinguish between rotavirus and non-rotavirus diarrhea in children Atika Akbari; Hasri Salwan; Achirul Bakri; Erial Bahar
Paediatrica Indonesiana Vol 56 No 6 (2016): November 2016
Publisher : Indonesian Pediatric Society

Background Distinguishing rotavirus from non-rotavirus diarrhea is helpful for managing the illness. However, definitively diagnosing rotavirus diarrhea from serology is difficult and expensive.Objectives To distinguish between the clinical manifestations of rotavirus and non-rotavirus diarrhea, and to assess the accuracy of using such clinical manifestations to predict the type of diarrhea in children.Methods A cross-sectional study was performed from April to October 2015 in all children less than five years of age who presented with acute diarrhea at the Pediatric Outpatient Clinic of the Department of Child Health and Emergency Department, Dr. Mohammad Hoesin and Bari Hospitals, Palembang, South Sumatera. Clinical manifestations were collected from history and physical examinations; stool specimens were examined by immunochromatography. Clinical parameters were analyzed by multivariate analysis, and scores given to each significant parameter. The accuracy of the scoring system based in these parameters was analyzed by means of receiver-operating characteristic (ROC) area under the curve (AUC).Results Of 184 children, 92 had rotavirus and 92 had non-rotavirus diarrhea. Multivariate analysis showed 3 clinical parameters commonly seen in the rotavirus diarrhea cases: male sex (OR 2.718; 95%CI 1.373 to 5.382), cough (OR 3.500; 95%CI 1.788 to 6.582), and yellow-greenish stool (OR 4.009; 95%CI 2.061 to 7.797). A scoring system was constructed based on the parameters: male (score of 1), cough (score of 2), and yellow-greenish stool (score of 3). From ROC analysis, the AUC was 0.755. Using a cut-off score of > 3, the sensitivity was 81.5%, specificity 51.1%, and PPV 62.5%.Conclusion Cough, yellow-greenish stool, and male are significant parameters for differentiating rotavirus from non-rotavirus diarrhea. A scoring system from these parameters is sensitive for predicting rotavirus vs. non-rotavirus diarrhea in children less than five years of age.

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