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All Journal Klinikal Sains (Jurnal Analis Kesehatan) JURNAL ANALIS LABORATORIUM MEDIK
Ira Pangesti
Universitas Al-Irsyad Cilacap
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology

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PERBANDINGAN NILAI TROMBOSIT, HEMATOKRIT DAN NLR ANTARA PASIEN DBD ANAK DAN DEWASA DI RUMAH SAKIT KHUSUS BEDAH MITRA ARIVA AJIBARANG Cahya Wulan Puspa Irmawati; Ira Pangesti; Yusuf Eko Nugroho
Klinikal Sains : Jurnal Analis Kesehatan Vol. 14 No. 1 (2026): Juni
Publisher : LPPM Universitas Abdurrab

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.36341/klinikal_sains.v14i1.7817

Abstract

Abstract Dengue Hemorrhagic Fever (DHF) is a viral infection caused by the dengue virus that remains a major public health problem in Indonesia, affecting various age groups with different clinical manifestations. Laboratory examinations such as platelet count, hematocrit level, and neutrophil-to-lymphocyte ratio (NLR) are important indicators to assess the severity of DHF. This study aimed to compare the values of platelet count, hematocrit, and NLR between pediatric and adult DHF patients at Mitra Ariva Ajibarang Surgical Hospital. The study used a quantitative method with a total sampling approach involving 40 medical record data of DHF patients from December 2024 to March 2025, consisting of 20 pediatric and 20 adult patients. Data were analyzed statistically using the Shapiro–Wilk test for normality and the independent t-test to examine intergroup differences. The results showed a significant difference (p < 0.05) in all three variables. The mean platelet count was higher in children (90.45×10³/µL) than in adults (62.20×10³/µL), while hematocrit and NLR values were higher in adults (47.05% and 3.56) compared to children (42.15% and 1.77). These findings indicate that adult patients experience more severe thrombocytopenia, hemoconcentration, and inflammatory responses than children. In conclusion, age significantly affects hematological parameters in DHF, with adult patients showing greater disease severity. Routine monitoring of platelet, hematocrit, and NLR values is essential for evaluating disease progression and preventing complications in DHF patients. Keywords: Dengue Hemorrhagic Fever, platelet, hematocrit, NLR, children, adults
KORELASI KADAR GLUKOSA DARAH DENGAN HITUNG JENIS LEUKOSIT PADA PASIEN DIABETES MELITUS TIPE 2 DI RSUD BAHTERAMAS KOTA KENDARI SULAWESI TENGGARA Wa Ode Surida; Imam Agus Faisal; Ira Pangesti
Jurnal Analis Laboratorium Medik Vol 10 No 2 (2025): JURNAL ANALIS LABORATORIUM MEDIK
Publisher : UNIVERSITAS SARI MUTIARA INDONESIA

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Abstract

Latar belakang: Diabetes melitus tipe 2 adalah penyakit metabolik kronis yang ditandai dengan hiperglikemia akibat resistensi insulin. Hiperglikemia kronis memicu peradangan sistemik yang memengaruhi sistem kekebalan tubuh. Oleh karena itu, pengukuran glukosa darah dan jumlah leukosit sangat penting untuk menilai status metabolik dan imunologi pasien. Tujuan: Penelitian ini bertujuan untuk mengetahui korelasi antara kadar glukosa darah dengan hitung jenis leukosit pada penderita DM tipe 2 di RSUD Bahteramas Kota Kendari Sulawesi Tenggara. Metode: Penelitian ini bersifat deskriptif analitik dengan pendekatan cross-sectional dengan menggunakan data sekunder dari 53 pasien DMT2 di RSUD Bahteramas Kota Kendari. Data berupa hasil pemeriksaan glukosa darah dan hitung jenis leukosit dari rekam laboratorium. Analisis dilakukan dengan uji Shapiro-Wilk dan korelasi Spearman Rank menggunakan SPSS. Hasil: Hasil penelitian ini menunjukkan bahwa sebagian besar pasien memiliki kadar glukosa darah ≥200 mg/dL. Jumlah neutrofil rata-rata lebih tinggi dibandingkan jenis leukosit lainnya. Hasil uji Spearman menunjukkan bahwa akumulasi neutrofil berkorelasi positif signifikan dengan kadar glukosa darah (r = 0,413; p = 0,002), sementara akumulasi eosinofil berkorelasi negatif signifikan (r = -0,290; p = 0,035). Kesimpulan: Terdapat hubungan yang signifikan antara kadar glukosa darah dengan beberapa jenis leukosit.
Co-Authors Cahya Wulan Puspa Irmawati Imam Agus Faisal Wa Ode Surida Yusuf Eko Nugroho