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All Journal Wahana Peternakan Livestock and Animal Research
Darmansyah Darmansyah
Faculty of Animal Husbandry, Hasanuddin University, Perintis Kemerdekaan KM 10, Makassar, 90245, Indonesia
Agriculture, Biological Sciences & Forestry Biochemistry, Genetics & Molecular Biology Veterinary

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PENGARUH PEMBERIAN EKSTRAK DAUN SAMBILOTO (ANDROGRAPHIS PANICULATA) TERHADAP TITER ANTIBODI AYAM RAS PETELUR Darmansyah; A. Mujnisa; Wempie Pakiding
Wahana Peternakan Vol. 7 No. 1 (2023): Wahana Peternakan
Publisher : Fakultas Peternakan Universitas Tulang Bawang Lampung

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jwputb.v7i1.710

Abstract

This experiment aims to determine the effect of sambiloto (Andrographis paniculata) leaf extract on antibody titers of Avian Influenza (AI) and Newcastle Disease (ND) of starter phase laying hens. This study used 100 Isa Brown strain laying hens. The cages used were 20 box cages of 60x50x50 cm size. The research method used is a completely randomized design (CRD) with 5 treatments (T1: 0%, T2: 0,5%, T3: 1%, T4: 1,5% and T5: 2%) of sambiloto (Andrographis paniculata) leaf extract and each treatment was repeated 4 times. The result of the analysis of variance showed that the treatment of sambiloto (Andrographis paniculata) leaf extract had no significant effect (P>0,05) on AI and ND antibody titers at 3, 4 and 5 weeks of age, but has a significant effect (P<0,05) on AI and ND antibody titers at 6 weeks of age. In conclusion, the administrasion of sambiloto (Andrographis paniculata) leaf extract in drinking water was able to accelerate the formation AI and ND antibody titers and was able to maintain higher antibody compared to the control treatment. The administration of sambiloto (Andrographis paniculata) leaf extract in drinking water was able to form and maintain AI and ND antibody titers. Keywords: antibody titers, avian influenza, laying hens, newcastke disease, sambiloto leaf extract
PENGARUH PEMBERIAN EKSTRAK AIR SAMBILOTO (Andrographis paniculata) TERHADAP PERTUMBUHAN DAN PROFIL LIPID AYAM PETELUR FASE STARTER: Effect of Andrographis (Andrographis paniculata) Aqueous Extract Administration on Growth Performance and Lipid Profile of Starter-Phase Laying Hens Darmansyah; A Mujnisa; Wempie Pekiding; Ummi Amanah; Riska Amelia; Triami Lestari; Fachrul Akbar
Wahana Peternakan Vol. 10 No. 2 (2026): Wahana Peternakan
Publisher : Faculty of Animal Science, University of Tulang Bawang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37090/jwputb.v10i2.3368

Abstract

The starter phase (0–6 weeks) is a critical period for laying hens that determines future production potential, characterized by the intensive development of the digestive system and vital organs. The global prohibition of Antibiotic Growth Promoters (AGP) necessitates the exploration of natural alternatives such as Sambiloto (Andrographis paniculata) phytobiotics. This study aims to empirically test the effect of Sambiloto Leaf Extract (SLE) dosage administered via drinking water on the growth performance and blood cholesterol profile. The research utilized a Completely Randomized Design (CRD) with five treatments: T1 (0% SLE), T2 (0.5%), T3 (1.0%), T4 (1.5%), and T5 (2.0% SLE). A total of 100 Isa Brown strain chicks were monitored over six weeks. Parameters observed included the blood cholesterol profile, drinking water intake (DWI), feed intake (FI), body weight gain (BWG) and feed conversion ratio (FCR). Results indicated that SLE administration significantly (P<0.05) reduced serum total cholesterol (up to 22.97%) and triglyceride levels (up to 28.36%) in high-dose groups (T3, T4, T5). This hypolipidemic effect is attributed to andrographolide inhibiting key enzymes in cholesterol synthesis. Conversely, SLE did not significantly affect (P>0.05) HDL or LDL levels, nor did it significantly impact growth performance parameters. However, the 2.0% dose (T5) demonstrated the most optimal positive trend, recording the highest BWG (11.24 g/bird/day) and the lowest FCR (2.57). It is concluded that SLE is well-tolerated and serves as an effective phytogenic feed additive to improve lipid profiles without compromising palatability or performance.   Keywords:  blood cholesterol, laying hens, phytobiotics, sambiloto, starter phase
Potency of green chiretta (Andrographis paniculata) leaf extract on antibody titers of laying chickens in the starter phase Darmansyah Darmansyah; A Mujnisa; Wempie Pakiding
Livestock and Animal Research Vol 22, No 2 (2024): Livestock and Animal Research
Publisher : Universitas Sebelas Maret

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20961/lar.v22i2.79503

Abstract

Objective: Andrographolide, biological component, is present in Green chiretta (Andrographis paniculata), as an immunomodulator and feed additive for laying hens, has been potential to be explored. The objective of this study is to investigate the impact of green chiretta (Andrographis paniculata) leaf extract on the levels of antibodies against Avian Influenza (AI) and Newcastle Disease (ND) in laying hens during the initial phase of egg production.Methods: A total of 100 Isa Brown strain laying hens were were used ini this study consisted of 20 box cages with 60x50x50 cm. The study employed a completely randomised design (CRD) with 5 treatments, i.e.  T0 = Drinking water without EEGC, T1 = Drinking water + 0.5% EEGC, T3 = Drinking water + 1% EEGC, T4 = Drinking water + 1.5% EEGC, T5 = Drinking water + 2% EEGC. The study was replicated four times for each treatment.Results: The analysis of variance revealed that the treatment with green chiretta leaf extract did not show a significant impact on AI and ND antibody titers at 3, 4, and 5 weeks of age. However, this treatment significant affect on AI and ND antibody titers at 6 weeks of age.Conclusions: The addition of green chiretta (Andrographis paniculata) leaf extract to drinking water boosts up the development of AI and ND antibody levels. It exhibited superior antibody levels in comparison to the control treatment. To clarify, applying green chiretta (Andrographis paniculata) leaf extract to drinking water can maintain AI and ND antibody levels.
Co-Authors A Mujnisa A Mujnisa A. Mujnisa Fachrul Akbar Riska Amelia Triami Lestari Ummi Amanah Wempie Pakiding Wempie Pakiding Wempie Pekiding