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All Journal Jurnal Zarah Jurnal Katalisator
Alfin Surya
Abdurrab University
Agriculture, Biological Sciences & Forestry Chemistry Education

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POTENTIAL OF MORINGA LEAF EXTRACT GEL (Moringa oleifera Lam.) AS AN ANTIBACTERIAL AGAINST Staphylococcus aureus CAUSES OF ACNE Asiska Permata Dewi; Alfin Surya; Fahma Shufyani
JURNAL KATALISATOR Vol. 11 No. 1 (2026): Jurnal Katalisator, Volume 11 No 1 April 2026
Publisher : LLDIKTI X Sumbar, Riau, Jambi, Kepri

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.62769/katalisator.v11i1.3535

Abstract

Moringa leaves (Moringa oleifera Lam.) can be utilized by the community to heal wounds, beriberi, and fever; have anti-inflammatory and analgesic properties; and treat skin disorders caused by bacteria. One of the skin diseases is acne, which is caused by the bacterium Staphylococcus aureus. The aim of this study is to determine the antibacterial activity of a gel made from moringa leaf extract against Staphylococcus aureus and to identify the secondary metabolite compounds of the extract through phytochemical screening. This research is a laboratory experiment that involves creating moringa leaf extract gel at concentrations of 2%, 4%, 6%, and 8% to inhibit the growth of Staphylococcus aureus. Antibacterial testing was conducted using the well diffusion and disc diffusion methods and analyzed using one-way ANOVA. Based on the results of the phytochemical screening, the extract contains flavonoid, alkaloid, saponin, tannin, and terpenoid compounds. The results of the study showed that the antibacterial activity of the gel with the well method at concentrations of 2%, 4%, 6% and 8% obtained an average inhibition zone of 7.68 mm; 8.8 mm; 9.18 mm; 9.55 mm. While with the well method, the average inhibition zone at concentrations of 2%, 4%, 6% and 8% was 8.55 mm; 9.03 mm; 9.17 mm; 9.88 mm. The ANOVA test analysis obtained a result of p = 0.000 smaller than α = 0.05 which means there is a significant difference in the average diameter of the inhibition zone between the treatment groups.
Serum Creatinine Levels among Motorcycle Workshop Mechanics in Carbon Monoxide-Prone Workplaces: A Photometric Study Alfin Surya; Maisyaroh; Dina fitriyah; Fatma; Hesti Marliza; Zaiyar
Jurnal Zarah Vol. 14 No. 2 (2026): October, 2026
Publisher : Fakultas Keguruan dan Ilmu Pendidikan, Universitas Maritim Raja Ali Haji

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.31629/zarah.v14i2.8299

Abstract

Motorcycle workshop mechanics work in environments where vehicle exhaust may accumulate, particularly in workshops located near dense traffic and with limited ventilation. Carbon monoxide (CO) is not directly measured in this study; therefore, daily working hours and years of employment are used as occupational indicators of possible long-term exposure. This descriptive cross-sectional study analyzed serum creatinine levels among 30 motorcycle workshop mechanics on Jalan Riau, Pekanbaru. Respondents were selected by purposive sampling based on predefined eligibility criteria. Venous blood was collected, processed into serum, and analyzed using an Optiva photometer with a Glory Diagnostics enzymatic creatinine kit at 510 nm. Descriptive statistics were used to summarize creatinine distribution by age, daily working duration, and length of employment. The results showed that 17 respondents (56.67%) had serum creatinine levels above the reference range (>1.3 mg/dL), while 13 respondents (43.33%) had normal levels (0.7-1.3 mg/dL). Increased creatinine levels were more frequent among mechanics working 12 hours/day (75%) than among those working 8 hours/day (20%), and were also more common in respondents aged 30 years or older and those with more than 10 years of employment. These findings suggest that mechanics with longer occupational contact in CO-prone workshop environments may have a higher proportion of elevated serum creatinine. However, because ambient CO or carboxyhemoglobin was not measured, the results should be interpreted as an occupational-health screening finding rather than evidence of direct causality. Improved ventilation, routine health monitoring, and occupational safety education are recommended.
Co-Authors Asiska Permata Dewi Dina Fitriyah Fahma Shufyani Fatma Hesti Marliza Maisyaroh Zaiyar, Zaiyar