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All Journal Journal of Dentistry Indonesia
Gottumukkala, Sruthima
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Dentistry

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Role of Titanium-Reinforced Platelet-Rich Fibrin in Periodontal Tissue Regeneration-A Systematic Review Manchala, Bhavya; Teju, Anurag; Pasupuleti, Mohan Kumar; Penmetsa, Gautami S; Gottumukkala, Sruthima; Lakshmi, Venkata
Journal of Dentistry Indonesia Vol. 31, No. 2
Publisher : UI Scholars Hub

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Objective: The objective of the study is to demonstrate the efficacy of Titanium reinforced platelet-rich fibrin (T-PRF) as the sole biomaterial amongst the biologics in periodontal regeneration of both soft and hard tissues. Methods: A PUBMED database search is conducted from August 2013 to August 2023. Only original articles, including Randomized controlled clinical trials, cross-sectional studies, prospective studies, and case-control studies, were included. The studies will be analyzed regarding the outcome of the association between T-PRF and periodontal regeneration of both hard and soft tissue. Results: From 35 articles identified, 8 RCTs were included. The use of T-PRF statistically significantly reduced PD and improved CAL and Radiographic bone fill. On soft tissue regeneration, better results in terms of PPD, CAL, RGML, Recession Depth, and an increase in thickness of attached gingiva are observed. Conclusion: The use of T-PRF significantly improved clinical outcomes in hard tissue regeneration and periodontal parameters, including the soft tissue outcomes in root coverage procedures.
Clinical Outcomes of Adjunctive Use of Oxygen-Releasing Formula in Non-Surgical Treatment of Periodontal Abscess Associated with Type 2 Diabetes Mellitus Kanakamedala, Anil Kumar; Gangireddy, Laxmi Kavya; Penmetsa, Gautami S; Gottumukkala, Sruthima; Pasupuleti, Mohan Kumar; Ramesh, Konathala Santhosh Venkata
Journal of Dentistry Indonesia
Publisher : UI Scholars Hub

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Background: This study aimed to evaluate the effectiveness of oxygen-releasing formula (ORF) as an adjunct in the non-surgical management of periodontal abscess in patients with type 2 diabetes mellitus. Methods: This split-mouth clinical trial was conducted on 14 patients with periodontal abscess with type 2 diabetes mellitus (T2DM), who were divided into a control group, nonsurgical periodontal therapy (NSPT) alone, and a test group (NSPT+ORF). Parameters such as Landry's healing index (HI) were evaluated at 1 week, 2 weeks, and 1 month. Probing pocket depth (PPD), clinical attachment level (CAL), and bleeding on probing presence or absence (BOP) were evaluated at baseline and 1 month. Results: There was statistical significance at one week in the test group in HI and BOP, but at 1 month, there was no statistical significance between the test and control groups. Mean PPD reduction and mean CAL gain were greater in the test group than in the control group at 1 month. Conclusion: Adjunctive use of ORF with non-surgical periodontal therapy showed promising improvements in early periodontal healing and clinical parameters in patients with T2DM. However, given the limited follow-up duration and the absence of significant intergroup differences for most outcomes, further well-designed studies are required to establish its clinical benefit.
Co-Authors Gangireddy, Laxmi Kavya Kanakamedala, Anil Kumar Lakshmi, Venkata Manchala, Bhavya Pasupuleti, Mohan Kumar Penmetsa, Gautami S Ramesh, Konathala Santhosh Venkata Teju, Anurag