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All Journal JOURNAL OF BIOMEDICAL SCINECES AND HEALTH
Martha Kaihena
Program Studi Sains Biomedis Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Pattimura Ambon, Indonesia
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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THE POTENTIAL OF ETHANOL EXTRACT FROM LANGSAT LEAVES (Lansium domesticum Var. Pubescent) IN CONTROLLING Aedes aegypti MOSQUITOES: A STUDY ON THE EFFECTIVENESS OF NATURAL SUBSTANCES AS MOSQUITO REPELLENTS Abdul M Ukratalo; Muhammad Nurhidayat Ichsan; Martha Kaihena; Dodikrisno Ekaputra Manery; Victory Osvaldo Pangemanan; Debby Dijola Moniharapon
Journal Of Biomedical Sciences and Health Vol. 1 No. 1 (2024): Bulan Februari 2024
Publisher : Universitas Karya Husada Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34310/y0zcq322

Abstract

The spread of diseases caused by the Aedes aegypti mosquito, such as dengue fever and Zika fever, continues to pose a serious threat to public health in many countries, particularly in tropical and subtropical regions. In an effort to address this problem, vector control is a key part of the strategy to prevent the transmission of these diseases. In recent decades, attention to the utilisation of natural materials as alternatives in vector control has increased. One potential source that needs to be explored is langsat leaves, which are known to have active compounds. Ethanol extracts of langsat leaves may contain compounds that can provide control effects against Aedes aegypti mosquito larvae. This study aims to assess the effectiveness of ethanol extract of langsat leaves in controlling Aedes aegypti mosquitoes, the vector of Dengue Fever disease. The extraction method was carried out using maceration technique with ethanol solvent. Bioactivity test was conducted through larvicidal bioassay against Aedes aegypti larvae. The results showed that ethanol extract of langsat leaves has larvicidal effect against Aedes aegypti mosquito larvae. The toxicity levels, both LC50 and LC90, indicate that the ethanol extract of langsat leaves has potential as a mosquito larvae control agent.  
REPRODUCTIVE HEALTH OPTIMIZATION: REMARKABLE BENEFITS OF AVOCADO JUICE IN ENHANCING PRODUCTION AND REDUCING SPERMATOZOAL ABNORMALITIES IN MICE EXPOSED TO CLOVE CIGARETTE SMOKE Martha Kaihena; Abdul M Ukratalo; Victory O Pangemanan; Dodikrisno E Manery
Journal Of Biomedical Sciences and Health Vol. 1 No. 1 (2024): Bulan Februari 2024
Publisher : Universitas Karya Husada Semarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.34310/5dvek558

Abstract

Cigarette smoke has the potential to disrupt hormonal balance, affect spermatogenesis processes, impair spermatozoa viability, and introduce toxic substances to spermatozoa. Avocado fruit contains proteins and vitamins such as vitamin A, B, B1, B2, E, and C, beta-carotene, linoleic acid, lecithin, calcium, iron, pantothenic acid, potassium, phosphorus, niacin, and natural plant oils. The presence of vitamin C and E in avocado is believed to enhance the quantity of Leydig cells and spermatozoa. This study aims to evaluate the potential of avocado juice in optimizing reproductive health in mice exposed to clove cigarette smoke. Male mice (Mus musculus), aged 2 months, weighing ±20g, were randomly divided into 5 groups: K- (negative control), K+ (positive control exposed to cigarette smoke without avocado juice), P1 (mice exposed to cigarette smoke and given avocado juice at a dose of 0.5 ml/20 g BW), P2 (mice exposed to cigarette smoke and given avocado juice at a dose of 0.7 ml/20 g BW), and P3 (mice exposed to cigarette smoke and given avocado juice at a dose of 0.9 ml/20 g BW). Cigarette smoke exposure was administered for 14 days. The results indicate that regular avocado juice consumption can enhance sperm production and reduce spermatozoa abnormalities in mice exposed to clove cigarette smoke. The clinical implications of these findings contribute to a deeper understanding of the potential of avocado juice as a supplement to improve reproductive health, particularly in environments exposed to clove cigarette smoke
Co-Authors Abdul M Ukratalo Abdul M Ukratalo Debby Dijola Moniharapon Dodikrisno E Manery Dodikrisno Ekaputra Manery Muhammad Nurhidayat Ichsan Victory O Pangemanan Victory Osvaldo Pangemanan