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All Journal Andalasian Livestock
Indri Juliyarsi
Department of Animal Products Technology, Faculty of Animal Science, Universitas Andalas
Agriculture, Biological Sciences & Forestry Chemistry Medicine & Pharmacology Veterinary

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The Potential and Mechanism of Probiotic as an Immunomodulator In Improving the Immune System to Support Body Health: A Review Doni Supadil; Sri Melia; Indri Juliyarsi; Ade Sukma
Andalasian Livestock Vol. 1 No. 2 (2024): ALive
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/alive.v1.n2.p96-113.2024

Abstract

Functional food is growing along with the increasing public awareness of body health. One of them is a probiotic functional food. Probiotics according to WHO/FHO (2001) are microorganisms added to products that will benefit the health of the body if consumed sufficiently, namely 106-108 CFU/ml. Probiotics have benefits in the digestive tract, on the other hand, probiotics need nutrients for their development, namely prebiotics which are expected to change the intestinal microflora and maintain balance in the gut. Probiotics have many benefits for the health of the body, one of which is to improve the immune system. Probiotics will interact with intestinal epithelial cells and be recognized by dendrites then produce IL-12 (Interleukin-12) and IFNγ (Inferon γ) by IDC (Interstitial Dendritic Cell) which can modulate the immune response system. The secretion of IFNγ (Inferon γ) by IDC proinflammatory cytokines has a dual function where IFNγ (Inferon γ) and IL-12 (Interleukin-12) circulate in the bloodstream to reach the epithelium and help alveolar macrophages and NK (Natural Killer) cells kill VR. Then pro-inflammatory cytokines IFNγ (Inferon γ) and IL-12 (Interleukin-12) secreted in the gut ecosystem after colonizing some probiotic strains help the immune system for specific Th1/Th17 (T helper cell) immune response. in addition, dendrite 4 cells will secrete IL-17 (Interleukin-17) which enhances the innate immune response. Probiotics can help B lymphocytes differentiate into plasma cells that can secrete specific immunoglobulin A. Some bacteria that can improve the immune system are Lactobacillus casei L431, Lactobacillus rhamnosus GG, Bifidobacterium longum Subsp Infantis R0033, Pediococcus acidilactici DS1, Lactobacillus plantarum HD02 and many more. In the future, probiotics can be developed as immunotherapy and other diseases such as cancer to improve the quality of human life.
Applications of Exopolysaccharides from Microorganisms in Livestock Food Products: A Review M. Adriansyah; Indri Juliyarsi; Sri Melia; Ade Sukma
Andalasian Livestock Vol. 3 No. 1 (2026): ALive
Publisher : Lembaga Penelitian dan Pengabdian kepada Masyarakat

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.25077/alive.v3.n1.p25-33.2026

Abstract

Exopolysaccharides (EPS) are biopolymers produced by various microorganisms and belong to the postbiotic group, which has great potential for application in food products, especially livestock products. In recent years, EPS has been increasingly studied owing to its ability to improve the functional properties of food, such as antioxidant, antibacterial, antibiofilm, immunomodulatory, and antitumor activities, as well as its potential as a prebiotic and agent for enhancing probiotic properties, while also improving product technology characteristics. From a food processing technology perspective, EPS play an important role in increasing viscosity, emulsion stability, texture, system stability, and gel formation ability, thereby contributing to improved product quality and stability. The advantage of EPS over live probiotics as a postbiotic lies in its higher stability under processing and storage conditions, making it more applicable in various food matrices. This review focuses on the effects of applying EPS produced by various microorganisms on the quality and functional properties of livestock food products, including milk, meat, eggs, and their processed products. Various research results have shown that the addition of EPS can improve physical stability, improve texture, extend shelf life, and increase functional value. The information provided discusses the influence of EPS produced by various types of microorganisms that have a positive impact on livestock products, such as milk, meat, eggs, and their processed products. Based on the results of this search, this is the first compilation to study the application of EPS in livestock products.
Co-Authors Ade Sukma Doni Supadil M. Adriansyah Melia, Sri