Article Per Year (5 Year)
p-Index From 2020 - 2025
0.23
P-Index
This Author published in this journals
All Journal Indonesian Journal of Biomedicine and Clinical Sciences
Gesit Purnama Giana Deta
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Health Professions Immunology & microbiology Medicine & Pharmacology Neuroscience

Published : 1 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 1 Documents
Search

 1 
The role of toxoplasma, rubella, cytomegalo virus, herpes virus infection as a risk factor for sensory hearing loss in children Bambang Udji Djoko Rianto; Veby Novri Yendri; Gesit Purnama Giana Deta
Indonesian Journal of Biomedicine and Clinical Sciences Vol 56 No 4 (2024)
Publisher : Published by Universitas Gadjah Mada

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.22146/inajbcs.v56i4.15721

Abstract

Toxoplasma, rubella, cytomegalovirus and herpes virus infection (TORCH) are syndromes that are considered risk factors for deafness.. This study aims to prove the risk factors which play the most significant role in the incidence of Sensory Hearing Loss in children. This used a case-control design, conducted at JIH Yogyakarta Hospital started from December 2023 to June 2024. All participants aged less than 5 years underwent oto-acoustic emission (OAE) examination, then determined presence or absence toxoplasma, rubella, cytomegalovirus and herpes virus using the electrochemiluminescence immunoassay (ECLIA) method. The inclusion criteria for the case group were: 1) patients diagnosed with sensory hearing loss (SHL), while the control group was normal. The exclusion criteria for the case and control groups there were non-infectious risk factors. Based on a type I error of 5% and type II error of 20%. The recommended sample size is 18 samples per group. Statistical analysis used stratified statistical analysis. The results of this study show that the combination of rubella + CMV had the greatest odds ratio (OR: 8) of sensory hearing loss, CMV OR: 0.62, herpes simplex virus OR: 0.28, combination of rubella + herpes simplex virus OR: 0.28, toxoplasma + CMV OR: 0.28, rubella obtained OR: 1 .5, and the combination of rubella + CMV + herpes simplex virus OR: 0.1. Based on these results the combination of rubella + CMV had the greatest OR compared to the combination of other risk factors and single risk factor.
Co-Authors Bambang Udji Djoko Rianto Veby Novri Yendri