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All Journal The International Journal of Medical Science and Health Research The Indonesian Journal of General Medicine
Dhimas Muhammad Suharyo
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Dentistry Health Professions Medicine & Pharmacology Nursing Public Health Veterinary

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A Comprehensive Literature Review of Effectiveness of Supplementary Calcium in Prevention of Preeclampsia Fajar Nurochman Sidik; Dhimas Muhammad Suharyo
The Indonesian Journal of General Medicine Vol. 7 No. 2 (2024): The Indonesian Journal of General Medicine
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/e3p9xq12

Abstract

Background: The literature on the effectiveness of supplementary calcium in preventing preeclampsia indicates a consensus among researchers about its potential benefits, although the evidence is nuanced and complex. Early discussions initiated by (López-Jaramillo et al., 2001) emphasized the necessity for large, controlled trials to establish a clearer understanding of the relationship between calcium supplementation and preeclampsia prevention. The variability in methodologies across studies complicates the ability to draw definitive conclusions, as highlighted by the inconsistencies in dosage, timing, and definitions of preeclampsia (removal of unmatched citation). Literature Review: The evidence presented by (Hofmeyr et al., 2014) indicates that low-dose calcium supplementation can significantly reduce the incidence of preeclampsia, particularly in populations at risk. This is echoed in the meta-analysis by (B. Adams et al., 2021), which highlighted the essential role of calcium in regulating blood pressure, particularly among women with low dietary intake. Furthermore, the exploration of calcium's physiological mechanisms, as discussed by (Perry et al., 2022), illustrates how calcium influences vascular function and may mitigate the risk of preeclampsia through various biological pathways. The findings from (Zavala et al., 2022) also affirm the protective effect of calcium supplementation, suggesting a substantial reduction in preeclampsia risk when higher doses are administered. Conclusion: In conclusion, while there is robust evidence supporting the role of calcium supplementation in preventing preeclampsia, the complexities surrounding dietary intake, individual risk factors, and the need for tailored supplementation strategies remain significant. Future research should aim to refine these recommendations and explore the optimal conditions under which calcium supplementation can be most effective in reducing the incidence of preeclampsia.
A Comprehensive Literature Review of Cost-Effectiveness of Uterine Tamponade Devices for The Treatment of Postpartum Hemorrhage Fajar Nurochman Sidik; Dhimas Muhammad Suharyo
The Indonesian Journal of General Medicine Vol. 7 No. 2 (2024): The Indonesian Journal of General Medicine
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/a0dwtt55

Abstract

Background: The literature on uterine tamponade devices for postpartum hemorrhage (PPH) reveals a complex interplay of efficacy, safety, and cost-effectiveness, particularly in low- and middle-income countries. Their modeling indicates that affordable UBT could significantly mitigate maternal morbidity and mortality, thus addressing a pressing healthcare challenge in resource-limited settings. Literature Review: Further expanding on this topic, (Pingray et al., 2021) conducted a systematic review that synthesizes various studies evaluating the effectiveness of uterine tamponade devices compared to standard care for refractory PPH. Their findings highlight the potential of these devices to reduce the necessity for surgical interventions and enhance maternal survival rates, presenting a strong case for the economic benefits of implementing UBT in clinical practice. Conversely, the article by (D. Weeks et al., 2022) brings a critical lens to the discussion, emphasizing the need for caution in adopting UBT widely. While acknowledging the high success rates associated with UBT, the authors raise concerns about the quality of the evidence, particularly the reliance on nonrandomized studies. They argue that the potential for increased need for further interventions post-UBT use necessitates a careful evaluation of the benefits versus risks. This perspective prompts a reevaluation of the implementation strategies for UBT, advocating for rigorous quality improvement measures within healthcare systems. Conclusion: Together, these articles provide a comprehensive understanding of the cost-effectiveness of uterine tamponade devices for PPH treatment. They highlight the urgent need for accessible interventions while emphasizing the importance of robust evidence and quality standards in their implementation. The discourse suggests that while UBT presents a promising solution, its successful integration into healthcare systems requires careful consideration of safety, efficacy, and the contextual challenges faced in diverse settings.
A Comprehensive Literature Review of Maternal And Perinatal Complications According To Maternal Age Fajar Nurochman Sidik; Dhimas Muhammad Suharyo
The International Journal of Medical Science and Health Research Vol. 7 No. 3 (2024): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/p68zv021

Abstract

Background: The literature on maternal and perinatal complications associated with advanced maternal age reveals a complex interplay of biological, medical, and socio-economic factors that contribute to adverse pregnancy outcomes. Studies consistently indicate that women aged 35 and older face heightened risks, including increased rates of cesarean sections, gestational diabetes, hypertensive disorders, and low birth weight infants (Aboneaaj, 2015); (C. Orazulike et al., 2015); (Schildberger et al., 2019). The deterioration of myometrial function with age, along with lifestyle factors such as obesity and smoking, are critical contributors to these complications (Aboneaaj, 2015). Literature Review: The examination of obstetric parameters shows a concerning trend: as maternal age increases, the likelihood of surgical interventions, particularly cesarean deliveries, also rises, especially among first-time mothers (Schildberger et al., 2019). This shift is contrasted by a decrease in spontaneous births, indicating that advanced maternal age is closely linked to a higher incidence of medical interventions (Schildberger et al., 2019); (Glick et al., 2021). Moreover, the intersection of maternal age with socioeconomic factors reveals that older mothers, particularly those from marginalized communities, experience compounded risks due to a lack of access to quality healthcare (Olapeju et al., 2021). This highlights the need for targeted healthcare interventions that address both age-related and socio-economic challenges to improve maternal and neonatal health outcomes (Olapeju et al., 2021). Conclusion: In conclusion, the body of literature underscores the critical importance of understanding the multifaceted risks associated with advanced maternal age. The studies collectively highlight the need for informed clinical practices and targeted interventions to mitigate adverse outcomes, ultimately aiming to enhance maternal and neonatal health in an era where advanced maternal age is increasingly common.
A Comprehensive Systematic Review of Nutritional Interventions For The Prevention of Maternal Morbidity Fajar Nurochman Sidik; Dhimas Muhammad Suharyo
The International Journal of Medical Science and Health Research Vol. 7 No. 3 (2024): The International Journal of Medical Science and Health Research
Publisher : International Medical Journal Corp. Ltd

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.70070/1edvdc37

Abstract

Background: The reviewed literature highlights the significant impact of nutritional interventions on preventing maternal morbidity and improving health outcomes for mothers and infants, particularly in low- and middle-income countries (LMICs). The systematic review by (Alemu Zerfu & Taddese Ayele, 2013) emphasizes the alarming prevalence of micronutrient deficiencies among pregnant women, particularly in regions like southern Asia and sub-Saharan Africa, where low birth weight and maternal undernutrition are critical issues. The authors advocate for multiple micronutrient supplementation as a vital strategy to enhance maternal health and reduce adverse pregnancy outcomes, while also calling for further research to address the variability in trial results. Literature Review: (Mousa et al., 2019) provide an overview of the increased nutritional demands during pregnancy, underscoring that dietary intake alone often cannot meet these needs. They advocate for supplementation and food fortification programs to address overlooked nutrients and improve maternal and fetal health. Similarly, (Oh et al., 2020) argue for prioritizing multiple micronutrient supplementation over traditional iron and folic acid alone, as it has shown significant benefits in reducing stillbirth and low birth weight, especially in LMICs. (S Lassi et al., 2020) further explore the effectiveness of antenatal macronutrient supplementation and food distribution programs, finding that balanced energy protein supplementation can significantly reduce perinatal mortality and improve birth weight. They emphasize the importance of addressing both micro- and macronutrient deficiencies to mitigate maternal and neonatal complications.  Conclusion: In conclusion, the synthesis of evidence from these studies illustrates the complexity of nutritional needs during pregnancy and the potential for targeted interventions to address these challenges. The urgent need for effective nutritional interventions, particularly in LMICs, is clear, as they play a crucial role in combating maternal morbidity and improving health outcomes for both mothers and infants.
Co-Authors Fajar Nurochman Sidik