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Potential antibacterial activity of Avicennia marina extract against pathogenic bacteria Rosa, Kamelia; Hidayah, Oktavia Nur; Sofyanti, Dhiya’ul Auliyah; Diswantoro, Reza Dwi; Zulkiflih, Mochammad Ivan; Fuadi, Mohamad Tanwirul
Journal of Marine Resources and Coastal Management Vol. 5 No. 1 (2024)
Publisher : UIN Sunan Ampel Surabaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.29080/mrcm.v5i1.2069

Abstract

Avicennia marina, a mangrove plant, is renowned for its medicinal properties, particularly its antibacterial potential. Phytochemical analysis of the plant revealed the presence of bioactive compounds such as alkaloids, terpenoids, and flavonoids, which are known to contribute to its antibacterial effects. This study investigates the antibacterial activity of Avicennia marina leaf extract against Staphylococcus aureus and Escherichia coli. The research employed three main methods: preparation of Nutrient Agar (NA) and Nutrient Broth (NB) as growth media, extraction of bioactive compounds from Avicennia marina leaves, and antibacterial testing at concentrations of 0.1 and 0.2 grams on each medium. The results showed that the leaf extract effectively inhibited the growth of Staphylococcus aureus when using NB, with inhibition zones measuring 6.47 mm and 12.26 mm, indicating a bacteriostatic effect. In contrast, no inhibition zones were observed when using NA, suggesting that the growth medium plays a critical role in determining antibacterial effectiveness. These findings underscore the significant potential of Avicennia marina leaf extract as a natural antibacterial agent, particularly against Staphylococcus aureus, and highlight the importance of selecting suitable media and testing methods. This study paves the way for future research into the development of Avicennia marina-based nutraceuticals and pharmaceuticals, with potential applications in healthcare and bacterial infection management.
Analisis Potensi Antioksidan Rumput Laut (Kappaphycus alvarezii dan Sargassum sp.) Sebagai Produk Body Lotion Rosa, Kamelia; Violando, Wiga Alif
Jurnal Kelautan Vol 18, No 3: Desember (2025)
Publisher : Department of Marine Sciences, Trunojoyo University of Madura, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21107/jk.v18i3.28551

Abstract

ABSTRAKRumput laut kaya akan senyawa bioaktif, terutama senyawa fenol dan turunannya yang berfungsi sebagai mekanisme pertahanan terhadap lingkungan ekstrim. Senyawa bioaktif ini memiliki aktivitas antioksidan yang ditemukan dalam rumput laut. Antioksidan dalam kosmetik berfungsi untuk mencegah oksidasi yang dapat merusak formulasi kosmetik dan menangkal efek buruk radikal bebas yang dapat menyebabkan kerusakan kulit seperti kemerahan, kekeringan, dan pecah-pecah. Tujuan penelitian ini adalah menganalisis kandungan antioksidan dalam body lotion berbahan dasar rumput laut (Kappaphycus alvarezii) dan (Sargassum sp.) menggunakan metode DPPH (2,2-diphenyl-1-picrylhydrazyl), dengan pengukuran yang dilakukan menggunakan spektrofotometer pada panjang gelombang 517 nm. Hasil penelitian menunjukkan bahwa body lotion berbahan dasar rumput laut (Kappaphycus alvarezii) dan (Sargassum sp.) mengandung antioksidan, yang ditunjukkan oleh perubahan warna dari ungu menjadi kuning pucat setelah didiamkan selama 30 menit. Hasil uji aktivitas antioksidan menunjukkan bahwa nilai IC₅₀ formulasi terbaik (F3) sebesar 36,36 ppm, yang termasuk kategori aktivitas antioksidan sangat kuat. Sebagai pembanding, nilai IC₅₀ F0 sebesar 24.237,50 ppm, F1 sebesar 49,80 ppm, dan F2 sebesar 49,75 ppm yang menunjukkan bahwa body lotion berbahan dasar rumput laut (Kappaphycus alvarezii) dan (Sargassum sp.) memiliki aktivitas antioksidan yang sangat kuat. Temuan ini memiliki signifikansi praktis bagi industri kosmetik sebagai alternatif bahan antioksidan alami yang ramah lingkungan, sekaligus berpotensi meningkatkan nilai tambah ekonomi masyarakat pesisir melalui pemanfaatan rumput laut lokal Kata kunci: Rumput laut, Antioksidan, body lotionABSTRACTSeaweed is rich in bioactive compounds, particularly phenolic compounds and their derivatives, which serve as defense mechanisms against extreme environments. These bioactive compounds possess antioxidant activity found in seaweed. Antioxidants in cosmetics function to prevent oxidation that can damage cosmetic formulations and counteract the adverse effects of free radicals that can cause skin damage such as redness, dryness, and cracking. The aim of this study is to analyze the antioxidant content in seaweed-based body lotion (Kappaphycus alvarezii) and (Sargassum sp.) using the DPPH (2,2-diphenyl-1-picrylhydrazyl) method, with measurements conducted using a spectrophotometer at a wavelength of 517 nm. The research results show that seaweed-based body lotion (Kappaphycus alvarezii) and (Sargassum sp.) contain antioxidants, as indicated by a color change from purple to pale yellow after being allowed to stand for 30 minutes. The antioxidant activity test showed that the IC₅₀ value of the best formulation (F3) was 36.36 ppm, which falls into the category of very strong antioxidant activity. For comparison, the IC₅₀ values of F0, F1, and F2 were 24,237.50 ppm, 49.80 ppm, and 49.75 ppm, respectively, indicating that the seaweed-based body lotion (Kappaphycus alvarezii and Sargassum sp.) possesses very strong antioxidant activity. This finding has practical significance for the cosmetics industry as an eco-friendly alternative source of natural antioxidants, while also offering the potential to enhance the economic value of coastal communities through the utilization of local seaweed. Keywords: Seaweed, Antioxidants, body lotion