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All Journal SCIENTIA JOURNAL International Journal of Islamic Education, Research and Multiculturalism (IJIERM) PHARMANAJA : PHARMACEUTICAL JOURNAL OF UNAJA
Evelyn Angie
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Religion Aerospace Engineering Arts Humanities Computer Science & IT Decision Sciences, Operations Research & Management Education Medicine & Pharmacology Nursing Public Health Other

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THE EFFECT OF ETHANOL EXTRACT OF ZIZIPHUS MAURITIANA LAM. LEAF ON ALLOXAN-INDUCED RAT Tcanty Indrianti; Ali Napiah Nasution; Evelyn Angie; Clarissa Lister; Veranyca Chiuman
International Journal of Islamic Education, Research and Multiculturalism (IJIERM) Vol 6 No 2 (2024)
Publisher : The Islamic Education and Multiculturalism Foundation

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.47006/ijierm.v6i2.348

Abstract

Bidara (Ziziphus mauritiana Lam.) or Indian jujube or ber is one Indonesian endemic plant which widely used as a traditional remedy in Indonesia and other Asian countries. Bidara leaves are commonly used as a remedy for diarrhea, liver diseases, and diabetes. This study aims to determine the effect of ethanol extract of bidara leaves (Z. mauritiana Lam.) on alloxan-induced male Wistar strain rat’s (Rattus norvegicus) liver. This is an experimental study with a randomized pretest-posttest with a control group design. This study involved 24 male Wistar strain rats (R. norvegicus) which were divided into 6 separate groups induced with alloxan and each group received a different intervention accordingly. Data in this study shows that ethanol extract of bidara leaves contains alkaloids, saponins, flavonoids, and glycoside compounds. This study also found that ethanol extract of bidara leaves at doses as low as 150 mg/kgBW managed to decrease the blood glucose, SGOT, and SGPT levels better than negative control and as effective as metformin. Escalation of SOD activity was also found to be directly proportional to dose increase, however, the highest concentration of MDA was also found in the highest dose of ethanol extract of bidara leaves. It can be concluded that ethanol extract from bidara leaves has anti-hyperglycemic (p<0.001) and hepatoprotective (p<0.05) effects, but the antioxidant properties cannot be determined according to this study’s data.
Hubungan antara Adiksi Internet, Tingkat Kecemasan, dan Kualitas Tidur dengan Kecerdasan Emosional Evelyn Angie; Pela Meyadsa; Zaimah Hilal; Ahmad Ferdian Shobur; Subang Aini Nasution
SCIENTIA JOURNAL Vol. 12 No. 2 (2023): SCIENTIA JOURNAL
Publisher : Universitas Adiwangsa Jambi

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Abstract

This study investigates the relationship between internet addiction, anxiety levels, and sleep quality with emotional intelligence among young adults in Jambi, Indonesia, in 2023. Utilizing a cross-sectional quantitative design, data were collected from 300 participants aged 18–25 years through validated questionnaires, including the Internet Addiction Test (IAT), the Hamilton Anxiety Rating Scale (HAM-A), the Pittsburgh Sleep Quality Index (PSQI), and the Emotional Intelligence Scale (EIS). The results revealed significant negative correlations between internet addiction and emotional intelligence (r = -0.43, p < 0.01), as well as between anxiety levels and emotional intelligence (r = -0.51, p < 0.01). Furthermore, poor sleep quality also exhibited a moderate negative relationship with emotional intelligence (r = -0.37, p < 0.01). These findings suggest that higher levels of internet addiction, increased anxiety, and lower sleep quality are associated with decreased emotional intelligence. The study highlights the importance of mental health and lifestyle management in the development of emotional regulation and psychological well-being in the digital era.
Pengaruh Ekstrak Daun Teh terhadap Kualitas Motilitas Spermatozoa Mencit Jantan yang Diberi Paparan Asap Rokok Meki Karolina; Edwin Lewis; Evelyn Angie; Sondang, Silitonga
PHARMANAJA : PHARMACEUTICAL JOURNAL OF UNAJA Vol. 2 No. 2 (2023): PHARMANAJA : PHARMACEUTICAL JOURNAL OF UNAJA
Publisher : Program Studi Farmasi UNAJA

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Abstract

Background: Cigarette smoke exposure is a major contributor to male infertility due to its oxidative stress effects on spermatozoa. Tea leaf extract is known to contain high levels of antioxidants that may counteract these effects. Objective: To determine the effect of tea leaf extract on sperm motility quality in male mice exposed to cigarette smoke. Method: This experimental study used 24 male mice divided into four groups: negative control, cigarette smoke exposure, and two treatment groups receiving cigarette smoke exposure along with 200 mg/kg BW and 400 mg/kg BW of tea leaf extract. Sperm motility was assessed using microscopic examination after 14 days of treatment. Results: The group exposed to cigarette smoke alone showed significantly decreased sperm motility. Administration of tea leaf extract at both doses improved sperm motility, with the 400 mg/kg BW group showing a motility value close to the negative control. Conclusion: Tea leaf extract significantly improves sperm motility in mice exposed to cigarette smoke, likely due to its antioxidant content.
Co-Authors Ahmad Ferdian Shobur Clarissa Lister Edwin Lewis Meki Karolina Nasution, Ali Napiah Pela Meyadsa Sondang, Silitonga Tcanty Indrianti Veranyca Chiuman Zaimah Hilal