Claim Missing Document
Check
Articles

Found 2 Documents
Search

Effectiveness of Secondary Prophylaxis with Benzathine Penicillin G in Preventing Recurrent Acute rheumatic fever and rheumatic heart disease in Brazilian Children: A Randomized Controlled Trial Sophia Lucille Rodriguez; Lucia Fernandez
Scientific Journal of Pediatrics Vol. 1 No. 2 (2023): Scientific Journal of Pediatrics
Publisher : Phlox Institute: Indonesian Medical Research Organization

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59345/sjped.v1i1.15

Abstract

Introduction: (ARF) and its sequela, (RHD), remain significant public health concerns in developing countries. Secondary prophylaxis with Benzathine Penicillin G (BPG) is the cornerstone of preventing recurrent ARF and progression of RHD. This study aimed to evaluate the effectiveness of BPG in preventing recurrent ARF and RHD in Brazilian children. Methods: A randomized controlled trial was conducted in a tertiary care hospital in Brazil. Children aged 5-15 years with a history of ARF and/or RHD were enrolled and randomly assigned to receive either BPG injections every 28 days or standard care (no BPG) for two years. The primary outcome was the incidence of recurrent ARF episodes. Secondary outcomes included the development of new or worsening RHD, echocardiographic parameters, and adverse events related to BPG. Results: A total of 200 children were enrolled (BPG group = 100, standard care group = 100). The median follow-up duration was 24 months. The incidence of recurrent ARF was significantly lower in the BPG group compared to the standard care group (4% vs. 18%, p < 0.001). The BPG group also demonstrated a reduced risk of developing new or worsening RHD (8% vs. 22%, p = 0.003). Echocardiographic parameters showed improvement in the BPG group, with a significant decrease in left atrial diameter and mitral regurgitation severity. Adverse events related to BPG were mild and infrequent. Conclusion: Secondary prophylaxis with BPG is highly effective in preventing recurrent ARF and RHD in Brazilian children. It should be considered a standard of care for all children with a history of ARF and/or RHD in endemic regions.
MULTIMODAL DISCOURSE IN MOBILE LANGUAGE LEARNING APPLICATIONS Lucia Fernandez
International Journal of Literature and Language Studies Vol. 5 No. 4 (2026): International Journal of Literature and Language Studies
Publisher : International Journal of Literature and Language Studies

Show Abstract | Download Original | Original Source | Check in Google Scholar

Abstract

This article investigates multimodal discourse in mobile language learning applications within the broader field of linguistics and applied language studies. The study uses lesson screens, feedback messages, icons, sounds, and visual prompts from three popular mobile language learning applications and applies multimodal discourse analysis focusing on image, colour, layout, sound, feedback, and learner positioning. The main finding is that apps used badges, progress bars, friendly characters, and immediate feedback to create motivation and guide learner behaviour. The article argues that language learning apps should be evaluated not only for linguistic content but also for the semiotic design of learning experience. The discussion is relevant to researchers, teachers, curriculum designers, and graduate students who need concise but systematic models of linguistic inquiry.