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All Journal Jurnal Penelitian dan Kajian Ilmiah Kesehatan Politeknik Medica Farma Husada Mataram Jurnal Sains Natural
Ustyawati, Jumari
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Biochemistry, Genetics & Molecular Biology Chemical Engineering, Chemistry & Bioengineering Immunology & microbiology Mathematics Medicine & Pharmacology Nursing Physics Public Health

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ANTIBACTERIAL ACTIVITY OF JAPANESE CAMBOJA (Adenium obesum) LEAF EXTRACT ON THE GROWTH OF THE BACTERI Sthaphylococcus aureus Lestari, Widya; Kurniawan, Edy; Ustyawati, Jumari; Mentari, Ika Nurfajri
Jurnal Penelitian dan Kajian Ilmiah Kesehatan Politeknik Medica Farma Husada Mataram Vol. 10 No. 1 (2024): April
Publisher : Politeknik Medica Farma Husada Mataram

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33651/jpkik.v10i1.692

Abstract

Staphylococcus aureus bacteria are microorganisms that can causing the most common infections such as skin infections. In the treatment of infections commonly use antibiotics, but there are often problems in use of antibiotics, leading to resistance. One way Preventing resistance is by looking for alternatives that are better cheap and efficient, one example is by using frangipani plants. (Adenium obesum). Japanese frangipani leaves themselves are believed to contain alkaloids, flavonoids and saponins that function as antibacterials. The purpose of this study was to determine the effect of giving Japanese frangipani leaf extract (Adenium obesum) on the growth of Staphylococcus aureus bacteria. This research method is a laboratory experiment by means of wells diffusion with concentrations of 50%, 25%, 15% and 10%. The results of this study indicate that there is no clear zone in each concentration. The conclusion is that Japanese frangipani leaves (Adenium obesum) are unable to inhibit the growth of Staphylococcus aureus bacteria.
Uji Efektivitas Ekstrak Batang Lengkuas (Alpinia Galanga) Terhadap Bakteri Streptococcus Pyogenes Secara In Vitro Al-Fariz, Rifqi; Kurniawan, Edy; Ustyawati, Jumari; Hijriani, Baiq Isti
JSN : Jurnal Sains Natural Vol. 2 No. 4 (2024): November
Publisher : Puslitbang Sekawan Institute Nusa Tenggara

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35746/jsn.v2i4.632

Abstract

Pyogenes merupakan bakteri patogen yang dapat menyebabkan penyakit mulai dari infeksi ringan hingga infeksi invasif yang mengancam jiwa. Penyakit yang disebabkan oleh bakteri streptococcus pyogens diobati dengan pemberian antibiotik seperti penisilin. Namun penggunaan antibiotik ini dengan dosis 500 mg dapat menimbulkan bakteri resisten akibat perubahan genetik, sehingga perlu dicari alternatif lain selain Streptococcus seperti menggunakan bahan alami yang berasal dari batang lengkuas misalnya. Batang lengkuas sendiri mengandung saponin, flaponoid, fenol yang berfungsi sebagai antibakteri. Tujuan penelitian ini adalah untuk mengetahui diameter zona hambat setiap konsentrasi batang lengkuas (Alpinia galanga) terhadap bakteri Streptococcus pyogenes. Metode penelitian ini menggunakan eksperimen laboratorium, menggunakan metode difusi sumur dengan konsentrasi 100%, 75%, 50%, 25%. Hasil penelitian ini menunjukkan bahwa tidak terbentuk zona bening pada semua konsentrasi. Kesimpulan penelitian ini adalah ekstrak batang lengkuas (Alpinia galanga) tidak mampu menghambat pertumbuhan bakteri Streptococcus pyogenes.
Co-Authors Al-Fariz, Rifqi BaiqIsti Hijriani Edy Kurniawan, Edy Hery Widijanto Mentari, Ika Nurfajri