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All Journal Jurnal Kesmas dan Gizi (JKG) UMI Medical Journal International Islamic Medical Journal
Hosanna, Cliffian
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Religion Humanities Biochemistry, Genetics & Molecular Biology Education Health Professions Immunology & microbiology Medicine & Pharmacology Public Health

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Role of Omega-3 Acids in Cardiovascular Health: A Literature Review Laksono, Sidhi; Hosanna, Cliffian
JURNAL KESMAS DAN GIZI (JKG) Vol. 7 No. 1 (2024): Jurnal Kesmas dan Gizi (JKG)
Publisher : Fakultas Kesehatan Masyarakat Institut Kesehatan Medistra Lubuk Pakam

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35451/jkg.v7i1.2239

Abstract

Introduction: Cardiovascular disease (CVD) is the leading cause of death in the world, with 27% of deaths in 2020 attributable to CVD. American Heart Association recommends adopting Mediterranean diet and eating 2-3 servings of fish to increase cardiovascular health and decrease morbidity and mortality caused by CVDs. This effect is thought to be attributed to Omega-3 content in those diets. But, conclusive evidence about the role of Omega-3 in cardiovascular disease hasn’t been reached. This paper aims to discuss further on to the topic of effects of Omega-3 on cardiovascular health. Method: Searching PubMed using keywords “Omega-3 Fatty Acids” AND “Cardiovascular”, and filtering relevant journals. Results: A literature review will be made from 6 choosen RCTs that fulfill all the criteria. Discussion: Bhatt et al concludes that supplementation of icosapent ethyl decreases CVD mortality, non-fatal MI, non-fatal stroke and unstable angina by 25%. But other RCTs fail to demonstrate said effects. Studies by Bowman et al, Kalstad et al, Manson et al, Nicholls et al, and Roncaglioni et al. concludes that supplementation of omega-3 fatty acid does not produce a significant change in CVD. These different findings across different studies may be caused by different doses of Omega-3 given, different baseline characteristics of patients and medications that masks the effects of Omega-3. Conclusion: Further studies are needed to determine the effects of omega-3 in CVD, but consumption of omega-3 appears to be safe and shows a slight reduction in CVD events based on a recent meta-analysis by Bernasconi et al.
Layanan Paliatif Pasien Gagal Jantung: Suatu Narasi Singkat Laksono, Sidhi; Hosanna, Cliffian
UMI Medical Journal Vol 9 No 2 (2024): UMI Medical Journal
Publisher : Fakultas Kedokteran Universitas Muslim Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33096/umj.v9i2.311

Abstract

Latar belakang: Gagal jantung merupakan penyakit dengan prevalensi cukup tinggi dengan angka mortalitas yang juga tinggi. Di samping itu, meskipun pengobatan dilakukan secara optimal, masih terdapat kemungkinan terjadinya perburukan. Isi: Dalam kasus gagal jantung lanjut, di mana fungsi atau struktur jantung telah mengalami kerusakan signifikan, penerapan terapi maksimal sesuai pedoman tidak lagi mampu mengatasi gejala. Populasi pasien gagal jantung lanjutan memiliki angka harapan hidup pasien yang lebih pendek. Gejala sesak dan nyeri juga akan mengganggu kualitas hidup pasien. Pasien dengan gagal jantung perlu dirujuk ke layanan paliatif sedini mungkin, terutama ketika prognosis pasien diketahui buruk dan harapan hidupnya rendah. Tinjauan literatur ini bertujuan untuk memberikan gambaran kajian ilmiah tentang layanan paliatif bagi pasien gagal jantung yang bertujuan untuk meringankan keluhan dan meningkatkan kualitas hidup pada pasien dan keluarga. Metodologi tinjauan literatur dengan melalui pencarian basis data medis pada jurnal kedokteran, pedoman, dan artikel medis. Kesimpulan: Peran layanan paliatif pada pasien dengan gagal jantung lanjutan telah direkomendasikan berbagai perkumpulan kardiologi di berbagai macam negara karena dapat membantu pasien mendapat pelayanan paling optimal sesuai dengan keinginan pasien.
Primary Percutaneous Coronary Intervention in a 24-hour PCI Capable Hospital in Indonesia Laksono, Sidhi; Hosanna, Cliffian; Angkasa, Irwan Surya; Nurbaeti, Putri
Jurnal Medis Islam Internasional Vol 7 No 1 (2025): June
Publisher : UNUSA Press

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.33086/iimj.v7i1.6531

Abstract

Introduction: Chest pain may be a symptom of a life-threatening disease such as S ST-Elevation Myocardial Infarction (STEMI). Immediate primary percutaneous coronary intervention (PPCI) is recommended for virtually all STEMI patients who present in a PCI-capable hospital. Objective: We would like to present data on Door-to-Balloon (DTB) times and the factors affecting it. Methods: This is a single-center retrospective study. Patients are STEMI patients, undergoing primary PCI from 1st January 2024 to 30th April 2024. Secondary data are obtained from the medical records and analyzed. Results: A total of 60 patients undergo PPCI during the study period. Patients are generally male patients, aged 53.67 years old, with 2 traditional cardiovascular risk factors, presenting to the emergency department (ED) with an average of 5.88 hours of chest pain. DTB time was 86.25 minutes during the study period. We identified the onset of chest pain and referred patients to be associated with DTB time. Referred patients had longer onset since chest pain but faster DTB time. We found no association between age, gender, presenting time, diagnosis, Killip class, and physician factor to significantly affect DTB time. Conclusions: We have identified factors that may help us improve our DTB time. Patient knowledge should also be improved to increase awareness of symptoms of chest pain, minimizing patient delay and improving total ischemic time. 
Co-Authors Angkasa, Irwan Surya Laksono, Sidhi Nurbaeti, Putri