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Characteristics and Clinical Outcomes of COVID-19 in ESRD Patients Undergoing Hemodialysis in Ngudi Waluyo Wlingi General Hospital in 2020-2022 Wijayanto, Fajar Hadi; Insanitaqwa, Aleyda Zahratunany; Mawaddah, Syarifiyana
Indonesian Journal of Kidney and Hypertension Vol 1 No 3 (2024): Volume 1 No. 3, December 2024
Publisher : PERNEFRI (PERHIMPUNAN NEFROLOGI INDONESIA)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.32867/inakidney.v1i3.156

Abstract

Background: The coronavirus disease (COVID-19) pandemic is a major threat to global health care. Comorbidities, including end-stage renal disease (ESRD), are related to an increased risk of severe infection and mortality. Objective: To assess determinants related to the clinical outcomes of COVID-19 in ESRD patients undergoing hemodialysis in Ngudi Waluyo Wlingi General Hospital in 2020-2022. Methods: This study included ESRD patients undergoing maintenance hemodialysis who were hospitalized at Ngudi Waluyo Wlingi General Hospital due to COVID-19 from May 2020 to February 2022. Clinical characteristics were investigated in relation to the severity and survival status. Results: A total of 26 patients (46.15% male) with a mean age of 52.27±13.65 years met the inclusion criteria. Of these, 42.3% had a mild infection, 23% had a moderate infection, 30.77% had a severe infection, and 3.8% had a critical infection. The mortality rate was 23.08%, with a mean length of stay of 15.19±7 days. Age, oxygen saturation, respiratory rate upon admission, lymphocyte and neutrophil levels, and neutrophil-to-lymphocyte ratio were significantly associated with COVID-19 severity. Length of stay was statistically influenced by respiratory rate upon admission. The mortality rate was correlated with the dialysis vintage, levels of hemoglobin, leukocytes, platelets, neutrophils, neutrophil-to-lymphocyte ratio, serum urea, serum creatinine, eGFR, and length of stay. Conclusion: COVID-19 in ESRD patients undergoing hemodialysis were more likely to have a poor prognosis. Identifying determinants is crucial for reducing morbidity and mortality.
NON-TRAUMATIC SUBARACHNOID HEMORRHAGE IN A 57-YEAR-OLD WOMAN WITH A LONG HISTORY OF VERTIGO: CASE REPORT Putri, Berlian Ristina; Satiadarma, Tiffany; Mawaddah, Syarifiyana; Indriyono, Andhy
Journal of Pain, Headache and Vertigo Vol. 6 No. 1 (2025): March
Publisher : PERDOSNI (Perhimpunan Dokter Spesialis Neurologi Indonesia Cabang Malang) - Indonesian Neurological Association Branch of Malang cooperated with Neurology Residency Program, Faculty of Medicine Brawijaya University, Malang, Indonesia

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jphv.2025.006.01.05

Abstract

Background: Indonesia has a high burden of stroke, became the number one cause of death. Among countries in Asia, Indonesia has the highest stroke mortality rate. Ischemic stroke, intracerebral hemorrhage, and subarachnoid hemorrhage were sequentially the highest to lowest prevalence of stroke. Subarachnoid hemorrhage most often causes severe headaches which patients may describe as the worst headache of their life, accompanied by vomiting and stiff neck. Focal neurological deficits to coma can appear depending on the severity of the disease. Vertigo is an alarming symptom that could indicate the existence of an unruptured intracranial aneurysms that predominantly causes non traumatic subarachnoid hemorrhage. Case: A 57-year-old woman came to the emergency room with decreased consciousness GCS E3V1M4 after falling in the bathroom 30 minutes before admission. Accompanying complaints were projectile vomiting. The patient had a history of chronic vertigo. History of hypertension, diabetes and smoking were denied. From physical examination neck stiffness, positive Brudzinski I, and right laterality were found. Non-contrast head CT scan findings showed subarachnoid and intraventricular hemorrhage. Leukocytosis (16,300/μL) and hypokalemia (2.8 mmol/L) were found in laboratory examinations. Mannitol, citicoline, acetazolamide, nimodipine, ketorolac, ondansetron, and ranitidine were given. The patient experienced clinical improvement after 18 hours of treatment in the ICU with GCS increase to E3V5M6. After 15 days of hospitalization, the patient experienced significant clinical improvement. Conclusion: Recognition of risk factors, early diagnosis, and management of subarachnoid hemorrhage are important in preventing morbidity and mortality and improving patient outcomes.