Article Per Year (5 Year)
p-Index From 2021 - 2026
0.702
P-Index
This Author published in this journals
All Journal Bioscientia Medicina : Journal of Biomedicine and Translational Research Bioscientia Medicina : Journal of Biomedicine and Translational Research
Valentin Widry Enggal
Unknown Affiliation
Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Neuroscience

Published : 4 Documents Claim Missing Document
Claim Missing Document
Check
Articles

Found 4 Documents
Search

 1 
Correlation between Troponin I Levels and Location of Acute Myocardial Infarction in ST-Elevation Myocardial Infarction Patients Tiara Monica; Valentin Widry Enggal
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 1 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i1.1172

Abstract

Background: Acute myocardial infarction (AMI) remains a leading cause of mortality in Indonesia. Cardiac troponin I (cTnI) is a highly sensitive and specific biomarker for AMI, and its levels may correlate with infarct location and prognosis. This study investigated the relationship between cTnI levels and the location of myocardial infarction in ST-elevation myocardial infarction (STEMI) patients. Methods: A cross-sectional study was conducted on 57 STEMI patients admitted to H. Abdul Manap Regional General Hospital in Jambi City from April 2022 to 2024. Patients were consecutively enrolled based on inclusion and exclusion criteria. cTnI levels were measured using a point-of-care testing (POCT) device. The correlation between cTnI levels and infarct location was analyzed using the Pearson correlation test. Results: The majority of patients were male (78.49%). The highest incidence of AMI was observed in the anterolateral location, with an average cTnI level of 12.16 ng/ml. A strong positive correlation was found between cTnI levels and the location of infarction (r = 0.891, p < 0.05). Conclusion: Higher cTnI levels are associated with specific AMI locations, particularly anterolateral infarctions. This finding highlights the importance of cTnI measurement in assessing AMI severity and potential prognosis.
Inflammatory Response in Stroke: A Comparative Leukocyte Analysis in Hemorrhagic and Ischemic Stroke Patients at a Single Center in Jambi, Indonesia Ardi Mardani; Ika Erna Uly Sirait; Tiara Monica; Valentin Widry Enggal
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 2 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i2.1199

Abstract

Background: Stroke remains a leading cause of mortality and morbidity worldwide. Inflammation plays a crucial role in the pathophysiology of both hemorrhagic and ischemic stroke. This study aimed to compare total leukocyte counts (TLC) in hemorrhagic and ischemic stroke patients to assess the inflammatory response and its potential implications for clinical outcomes. Methods: This retrospective study analyzed 74 stroke patients admitted to Abdul Manap Regional Hospital, Jambi, Indonesia, between January 2023 and December 2023. Patients were categorized into hemorrhagic (intracerebral hemorrhage) and ischemic stroke groups based on neuroimaging findings (CT scan or MRI). Demographic data, stroke severity (NIHSS score), and TLC obtained within 24 hours of admission were recorded. Independent t-tests and Mann-Whitney U tests were used for statistical analysis. Results: The study included 38 ischemic and 36 hemorrhagic stroke patients. The mean TLC was significantly higher in the hemorrhagic stroke group (11.4 ± 3.5 x10^9/L) compared to the ischemic stroke group (9.5 ± 2.8 x10^9/L) (p = 0.021). No significant correlation was found between TLC and stroke severity (NIHSS score) in either group. Conclusion: Hemorrhagic stroke patients exhibited a more pronounced early inflammatory response as evidenced by elevated TLC compared to ischemic stroke patients. Further research is needed to explore the prognostic value of TLC and the potential role of anti-inflammatory therapies in stroke management.
Correlation between Troponin I Levels and Location of Acute Myocardial Infarction in ST-Elevation Myocardial Infarction Patients Tiara Monica; Valentin Widry Enggal
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 1 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i1.1172

Abstract

Background: Acute myocardial infarction (AMI) remains a leading cause of mortality in Indonesia. Cardiac troponin I (cTnI) is a highly sensitive and specific biomarker for AMI, and its levels may correlate with infarct location and prognosis. This study investigated the relationship between cTnI levels and the location of myocardial infarction in ST-elevation myocardial infarction (STEMI) patients. Methods: A cross-sectional study was conducted on 57 STEMI patients admitted to H. Abdul Manap Regional General Hospital in Jambi City from April 2022 to 2024. Patients were consecutively enrolled based on inclusion and exclusion criteria. cTnI levels were measured using a point-of-care testing (POCT) device. The correlation between cTnI levels and infarct location was analyzed using the Pearson correlation test. Results: The majority of patients were male (78.49%). The highest incidence of AMI was observed in the anterolateral location, with an average cTnI level of 12.16 ng/ml. A strong positive correlation was found between cTnI levels and the location of infarction (r = 0.891, p < 0.05). Conclusion: Higher cTnI levels are associated with specific AMI locations, particularly anterolateral infarctions. This finding highlights the importance of cTnI measurement in assessing AMI severity and potential prognosis.
Inflammatory Response in Stroke: A Comparative Leukocyte Analysis in Hemorrhagic and Ischemic Stroke Patients at a Single Center in Jambi, Indonesia Ardi Mardani; Ika Erna Uly Sirait; Tiara Monica; Valentin Widry Enggal
Bioscientia Medicina : Journal of Biomedicine and Translational Research Vol. 9 No. 2 (2025): Bioscientia Medicina: Journal of Biomedicine & Translational Research
Publisher : HM Publisher

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.37275/bsm.v9i2.1199

Abstract

Background: Stroke remains a leading cause of mortality and morbidity worldwide. Inflammation plays a crucial role in the pathophysiology of both hemorrhagic and ischemic stroke. This study aimed to compare total leukocyte counts (TLC) in hemorrhagic and ischemic stroke patients to assess the inflammatory response and its potential implications for clinical outcomes. Methods: This retrospective study analyzed 74 stroke patients admitted to Abdul Manap Regional Hospital, Jambi, Indonesia, between January 2023 and December 2023. Patients were categorized into hemorrhagic (intracerebral hemorrhage) and ischemic stroke groups based on neuroimaging findings (CT scan or MRI). Demographic data, stroke severity (NIHSS score), and TLC obtained within 24 hours of admission were recorded. Independent t-tests and Mann-Whitney U tests were used for statistical analysis. Results: The study included 38 ischemic and 36 hemorrhagic stroke patients. The mean TLC was significantly higher in the hemorrhagic stroke group (11.4 ± 3.5 x10^9/L) compared to the ischemic stroke group (9.5 ± 2.8 x10^9/L) (p = 0.021). No significant correlation was found between TLC and stroke severity (NIHSS score) in either group. Conclusion: Hemorrhagic stroke patients exhibited a more pronounced early inflammatory response as evidenced by elevated TLC compared to ischemic stroke patients. Further research is needed to explore the prognostic value of TLC and the potential role of anti-inflammatory therapies in stroke management.
Co-Authors Ardi Mardani Ika Erna Uly Sirait Tiara Monica