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All Journal Universa Medicina Science Midwifery
Awan, Syuma Adhy
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Dentistry Health Professions Immunology & microbiology Medicine & Pharmacology Nursing Public Health Veterinary

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Analyzing the relationship between dietary factors and anemia to improve preventive behavior in adolescent girls in Denpasar Wibawa, Anak Agung Ngurah Alit Dwi Nanda; Weta, I Wayan; Ani, Luh Seri; Awan, Syuma Adhy
Science Midwifery Vol 12 No 6 (2025): February: Health Sciences and related fields
Publisher : Institute of Computer Science (IOCS)

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.35335/midwifery.v12i6.1799

Abstract

Adolescents are at risk of developing anemia related to an unbalanced diet, habits of consuming low-iron foods, and substances that inhibit iron absorption, such as tea or coffee. Based on this, this study is aimed at finding out the relationship between diet and anemia status in adolescent girls. A cross-sectional study was conducted on 91 female students who were selected by the proportional random sample method. The research was conducted at SMAN 4 Denpasar-Bali, Indonesia. Hemoglobin level data was measured using a hemoglobinometer. Anemia is defined by a hemoglobin level of less than 12 g/dL. Diet and nutrient intake data were collected by questionnaire method using a quantitative food frequency questionnaire. The data were analyzed univariate and bivariate. The Mann-Whitney U test was carried out to determine factors related to anemia in adolescent girls. The results of the study found that the proportion of anemia in adolescent girls was 38.5%. Vitamin C intake was found to be related to anemia (p value <0.05). Meanwhile, protein intake, iron, fiber, frequency of meals and menstrual blood loss score (KDM) were found not to be related to anemia status (p>0.05). It can be concluded that a diet high in vitamin C is associated with anemia in adolescent girls. The results of this study contribute to the prevention of anemia through dietary improvements in adolescent girls, so it is recommended for adolescent girls to maintain a balanced diet to meet nutritional needs, including the need for iron.
Effect of astaxanthin supplementation on oxidative stress in adult women with polycystic ovary syndrome: a systematic review and meta-analysis of randomized controlled trials Pratiwi, Donna; Harimawan, Agustinus I Wayan; Weta, I Wayan; Sumartini, Ni Ketut; Awan, Syuma Adhy; Sutadarma, I Wayan Gede
Universa Medicina Vol. 45 No. 1 (2026)
Publisher : Faculty of Medicine, Universitas Trisakti

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.18051/UnivMed.2026.v45.125-134

Abstract

BackgroundPolycystic ovary syndrome (PCOS) can cause significant morbidity through fertility disorders and most often found in the productive age. Recent research suggests that oxidative stress plays an important role in the pathogenesis of PCOS. Astaxanthin (AST) has broad protective effects, particularly in the regulation of antioxidant and anti-inflammatory activity. The objective of this systematic review and meta-analysis was to evaluate the efficacy of AST supplementation on PCOS management. MethodsA systematic literature search was conducted in PubMed, Scopus, Science Direct, and Cochrane Library from January 2020 to March 2025. Randomized controlled trials (RCTs) assessing astaxanthin supplementation in adult women with PCOS were included. Outcomes of interest were malondialdehyde (MDA), superoxide dismutase (SOD), and total antioxidant capacity (TAC). Data were analyzed using Review Manager (RevMan) version 5.4.1. Pooled effects were calculated as mean differences (MDs) with 95% confidence intervals (CIs).  ResultsFour RCTs involving 194 participants were included. Astaxanthin supplementation significantly reduced MDA levels (MD −0.670; 95% CI −1.070 to −0.270; p = 0.001; I² = 93%) and significantly increased TAC levels (MD 0.030; 95% CI 0.000 to 0.060; p = 0.030; I² = 76%). No significant effect was observed on SOD levels (MD 0.025; 95% CI −0.850 to 1.350; p = 0.660; I² = 57%). The overall risk of bias across included studies was low. ConclusionThis systematic review shows that AST supplementation significantly reduced lipid peroxidation in women with PCOS. These findings suggest that AST may serve as potential adjuvant antioxidant therapy in PCOS management.
Co-Authors Harimawan, Agustinus I Wayan I Wayan Gede Sutadarma I Wayan Weta Luh Seri Ani Pratiwi, Donna Sumartini, Ni Ketut Wibawa, Anak Agung Ngurah Alit Dwi Nanda