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All Journal Muhammadiyah Medical Journal
Wibowo, Resna Murti
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Biochemistry, Genetics & Molecular Biology Immunology & microbiology Medicine & Pharmacology Nursing Public Health

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Clinical Characteristics of Acute Kidney Injury in COVID-19 Patients Nisrina, Nada; Wibowo, Resna Murti
Muhammadiyah Medical Journal Vol 4, No 1 (2023): Muhammadiyah Medical Journal (MMJ)
Publisher : Faculty of Medicine and Health Universitas Muhammadiyah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24853/mmj.4.1.1-7

Abstract

Background: Coronavirus Disease 2019 (COVID-19) is one of the infectious diseases that exist in Indonesia. Not only infects the lungs, but this virus can also infect other organs such as the kidneys. In addition, the process of viral infection causes cell hypermetabolism, which can increase the workload of the kidneys in excreting metabolic waste. In the end, the damage caused by the virus can cause Acute Kidney Injury (AKI). It is necessary to know the prevalence and characteristics of this event. Purposes: This study aims to provide an overview of AKI's prevalence and clinical features in COVID-19 patients. Methods: This was a descriptive study that used patient medical records for the period April-September 2021. The univariate analysis data showed a characteristic frequency distribution of age, gender, comorbidity, hospitalization duration, and urea creatinine rate. Results: The incoming samples based on the inclusion and exclusion criteria were 44 samples. In COVID-19 patients, complications of AKI were found in adults, as much as 68.2% of both men and women had a percentage of 50%, the most common comorbid was hypertension 30.8% with a hospitalization duration of 1-10 days 43.2% and an average increase in urea 79.68 mg/dL and creatinine average 2,859 mg/dL. Conclusion: Based on patient characteristics, the results showed that more COVID-19 patients with acute kidney injury complications occurred in adult patients, with no difference in prevalence between males and females, with comorbid hypertension and length of hospitalization less than ten days.
Comparison of Death Rates between COVID-19 Patients with Type 2 Diabetes Mellitus and without Type 2 Diabetes Mellitus Widianita, Nadhila; Wibowo, Resna Murti
Muhammadiyah Medical Journal Vol 4, No 1 (2023): Muhammadiyah Medical Journal (MMJ)
Publisher : Faculty of Medicine and Health Universitas Muhammadiyah Jakarta

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.24853/mmj.4.1.45-51

Abstract

Background: Coronavirus Disease 2019 (COVID-19) is an acute airway infection caused by coronavirus, and one of the comorbid diseases that can increase the severity and mortality of COVID-19 is diabetes mellitus. Purposes: To compare mortality rates in COVID-19 patients with type 2 DM and those without type 2 DM at Bunda Margonda General Hospital, Depok Jawa Barat. Methods: This study is a comparative study with a cross-sectional design obtained from secondary data in the form of medical record data at Bunda Margonda Depok Hospital in January-December 2021. The collection was carried out using the total sampling technique. Data were tested using the Cross Tabulation (crosstab) test. Results: Of the 144 COVID-19 patients, 56.9% of COVID-19 patients died with type 2 DM, while 43.1% died without type 2 DM comorbidity. Based on the comparison results of the mortality rate of COVID-19 patients accompanied by Type 2 DM and those not accompanied by Type 2 DM, the P value is 0.127, which means there was no relationship between mortality rate and Type 2 DM status. The mortality rate male gender is more likely to die in COVID-19 cases with an incidence of (53.5%), while in women (46.5%). Conclusion: Patients with comorbidities are more susceptible to Covid-19, and their symptoms are divided into mild, moderate, and severe. In patients with comorbid diabetes mellitus, there will be an increased occurrence of Covid-19 disease due to decreased immune function, resulting in a longer healing time in patients with diabetes mellitus.
Co-Authors NISRINA, NADA Widianita, Nadhila