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Analysis of the Relationship between ALBI Score and APRI Score on Severity, Length of Treatment and Mortality in COVID-19 Patients at Dr. Saiful Anwar Hospital, Malang Wibowo, Bogi; Mahendra, Aditya; Ibad, Ahmad; Santoso, Dimas; Eldatarina, Helsa
Clinical and Research Journal in Internal Medicine Vol. 5 No. 2 (2024): Volume 5 No 2, November 2024
Publisher : Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.crjim.2024.005.02.02

Abstract

Background: Covid-19 is an infectious disease caused by the SARS-CoV-2 virus and has resulted in more than 3.8 million deaths worldwide. Covid-19 can cause multiorgan complications, including hepatobiliary organs. Many assessments have been used to determine the severity and prognosis of hepatobiliary disorders, such as the Albumin Bilirubin (ALBI) score and the AST-platelet ratio index (APRI) score. Aim: This study aims to determine the relationship between the ALBI score and APRI score with severity, length of treatment, and mortality in COVID-19 infection. Methods: We conducted a case-control study in a population of adult patients with confirmed COVID-19 who were hospitalized at RSSA in the period January-December 2022. Patients with hepatobiliary and autoimmune disorders were excluded from the sample population for further analysis. Albumin, bilirubin, SGOT, and platelet levels were measured at the beginning of the patient's hospitalization. The correlation between variables was analyzed using the Rank-Spearman test with SPSS 27. Results: The study subjects' characteristics showed that most patients were more than 60 years old (66.67%). Based on the severity of the disease, five patients (16.67%) were mild, ten patients (33.33%) were moderate, and 15 patients (50%) were severe. Of the 30 patients, 16 recovered (53.33%) and 14 died (46.67%). The majority of subjects did not require treatment in the ICU (66.67%). The results of the Rank-Spearman Test showed that the ALBI score [R=0.372; p=0.043 (p<0.05)] and APRI score [R=0.409; p=0.025 (p<0.05)] were significantly correlated with the mortality of Covid-19 patients but not with the severity and length of treatment. Conclusion: The conclusion of this study shows that ALBI score and APRI score have a significant relationship with mortality in COVID-19 patients and have the potential to be further studied as predictive factors in assessing the prognosis of COVID-19 patients.
Investigating the connection between age progression and erectile dysfunction incidence in chronic kidney disease patients undergoing hemodialysis Widiaputro, Dandi; Suwito, Heru; Eldatarina, Helsa; Firmansah, Wahyu; Akbar, Muhamad; Wattimury, Rosmince; Rahardja, Ketut; Haryanto, Dheni; Gunawan, Atma
Deka in Medicine Vol. 1 No. 2 (2024): August 2024
Publisher : PT. DEKA RESEARCH INSTITUTE

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.69863/dim.2024.e210

Abstract

BACKGROUND: Erectile dysfunction is frequently observed in patients with chronic kidney disease (CKD), especially in the elderly population. However, studies have presented diverse outcomes on this matter. OBJECTIVES: To assess the correlation between age progression and the prevalence of erectile dysfunction in chronic kidney disease patients receiving hemodialysis. METHODS: The study employed a retrospective design and was conducted at RSUD Dr. Saiful Anwar, Malang, during June-July 2022. Data collection involved retrieving age, the erection hardness score (EHS), and baseline characteristics from medical records. Statistical analysis focused on assessing the correlation between age and erectile dysfunction using linear regression. RESULTS: The study population consisted of 59 patients with erectile dysfunction and 61 patients without erectile dysfunction. The primary findings highlighted a substantial and moderately negative association between age and the EHS score, which serves as a key indicator of erectile function. The results suggested that as individuals aged, there was a noticeable trend towards a decrease in the EHS score, implying a decrease in erectile capacity. CONCLUSION: Our findings emphasize the crucial importance of age as a determining factor in the development of erectile dysfunction.