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All Journal Jurnal Mahasiswa Ilmu Kesehatan Jurnal Riset Ilmu Kesehatan Umum dan Farmasi Intellektika: Jurnal Ilmiah Mahasiswa
Feni Atika Tsuroyya
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Arts Humanities Computer Science & IT Decision Sciences, Operations Research & Management Economics, Econometrics & Finance Education Health Professions Nursing Public Health Social Sciences

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Tinjauan Organ Jantung sebagai Pusat Kehidupan dalam Sistem Kardiovaskular Feni Atika Tsuroyya; Khotimah Nur Ramadhani; Elsa Oktavia Ramadhani; Liss Dyah Dewi Arini
Jurnal Mahasiswa Ilmu Kesehatan Vol. 3 No. 1 (2025): Jurnal Mahasiswa Ilmu Kesehatan
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/jumkes.v3i1.2010

Abstract

The heart is a vital organ that plays a crucial role in the circulatory system, responsible for pumping oxygen-rich blood and nutrients throughout the body and returning blood containing carbon dioxide to the lungs. Anatomically, the heart consists of four chambers. The coronary vascular system supplies oxygen and nutrients to the heart muscles. The physiology of the heart involves the cycle of heart muscle contraction (systole) and relaxation (diastole), heart rate regulation, and the electrical conduction system that coordinates the heartbeat. Coronary artery disease (CAD) is a disorder of the coronary blood vessels due to atherosclerosis, causing narrowing or blockage of the arteries, hindering blood flow, and leading to ischemia. Prevention of CAD can be done by maintaining a healthy diet, exercising regularly, avoiding smoking, and controlling blood pressure, cholesterol, and blood sugar levels. Understanding the anatomy, physiology, and coronary artery disease is essential for maintaining heart health and preventing cardiovascular disorders.
Studi Mikroskopis Fase-Fase Mitosis pada Sel Akar Bawang Merah (Allium cepa) sebagai Model Pembelajaran Biologi Sel Margaretha Alesandria Natasya Weka; Feni Atika Tsuroyya; Septi Puspita Kurniawati; Azlinatul Lulu Kharolaini; Pramai Sheila Eka Khoireina; Liss Dyah Dewi Arini
Intellektika : Jurnal Ilmiah Mahasiswa Vol. 3 No. 4 (2025): Intellektika : Jurnal Ilmiah Mahasiswa
Publisher : STIKes Ibnu Sina Ajibarang

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.59841/intellektika.v3i4.3161

Abstract

This study aims to observe the phases of mitosis in the meristem cells of shallot roots (Allium cepa) through microscopic observation as part of the Cell Biology learning model. Mitosis is an important part of the cell cycle that plays a role in growth, tissue repair, and asexual reproduction in organisms. A deep understanding of the mitosis process is an important foundation in various branches of biology, including genetics, biotechnology, and histology. Shallot roots were chosen because they have actively dividing meristem tissue at the root tip,as well as a large and transparent cell structure that facilitates the staining and observation process. Preparation was carried out by soaking the onion roots in a solution of acetic acid and alcohol for fixation,then staining with acetocarmine acid so that the chromosomes are clearly visible. The process of crushing the root tip and pressing it on a glass object (squash method) was used to expand the observation area. A light microscope with a magnification of 400x and 1000x was used to identify the division phases. Observation results show the presence of all phases of mitosis, namely prophase (nucleolus and nuclear membrane begin to disappear,chromosomes condense), metaphase (chromosomes line up at the equator), anaphase (chromatids separate to opposite poles), and telophase (nuclear membrane and two daughter cell nuclei re-form). Visual documentation in the form of microscopic photographs and descriptive tables clarify the identification of these phases, thus facilitating student understanding.From a pedagogical perspective, this microscopic practicum-based learning has been proven to improve students' observational skills, laboratory skills, and conceptual understanding of cell division. Students not only memorize theories, but directly experience the scientific process through exploration and discussion of observation results. Evaluation of learning outcomes is carried out through post-practicum quizzes and student worksheets, showing an increase in understanding scores of more than 30%.
Hubungan antara Kerusakan DNA dan Mekanisme Perbaikan Seluler: Tinjauan Literatur Azizah Zahra Nur Fitria; Margaretha Alesandria Natasya Weka; Azlinatul Lulu Kharolaini; Desi Rahmasari; Pramai Sheila Eka Khoireina; Feni Atika Tsuroyya; Septi Puspita Kurniawati; Tyara Avrilyanti Ghea Indriansyah; Liss Dyah Dewi Arini
Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) Vol. 4 No. 2 (2026): April : Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF)
Publisher : LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.57213/jrikuf.v4i2.972

Abstract

DNA damage is a fundamental biological phenomenon that occurs due to endogenous and exogenous factors such as radiation, chemical exposure, and replication errors. If not properly repaired, DNA damage can lead to genomic instability, mutations, and the development of various diseases, including cancer. This literature review aims to examine the relationship between DNA damage and cellular repair mechanisms in maintaining genomic integrity. The method used in this study is a literature review of national scientific journals that discuss types of DNA damage, molecular markers of DNA damage, and cellular repair pathways. The findings indicate that cells possess complex and coordinated DNA repair systems, including base excision repair, nucleotide excision repair, mismatch repair, and double-strand break repair mechanisms, which play crucial roles in preserving cellular stability. The effectiveness of these repair mechanisms is influenced by the type and extent of DNA damage. Understanding the interaction between DNA damage and repair pathways provides important implications for the development of disease prevention strategies, diagnostic biomarkers, and therapeutic approaches in molecular biology and medical sciences.
Co-Authors Azizah Zahra Nur Fitria Azlinatul Lulu Kharolaini Desi Rahmasari Elsa Oktavia Ramadhani Khotimah Nur Ramadhani Liss Dyah Dewi Arini Margaretha Alesandria Natasya Weka Pramai Sheila Eka Khoireina Septi Puspita Kurniawati Tyara Avrilyanti Ghea Indriansyah