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All Journal PELS (Procedia of Engineering and Life Science)
Shaker, Maha Mahmoud
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Computer Science & IT Control & Systems Engineering Electrical & Electronics Engineering Engineering

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Study of Some Immune Changes That Related to Leishmania (CL) Infection Shaker, Maha Mahmoud
Procedia of Engineering and Life Science Vol. 6 (2024): The 3rd International Scientific Meeting on Health Information Management (3rd ISMoHI
Publisher : Universitas Muhammadiyah Sidoarjo

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21070/pels.v6i0.2063

Abstract

Cutaneous leishmaniasis is an infection of the skin. The symptoms graduated causes bumps that after that turn into ulcers (large) in the future. Healing may take a long time. Symptoms begin within weeks or may be months after bite of sand fly.This study was conducted in the city of Hilla. This study included 90 patients who were selected from visitors to private clinics. These study participants were then divided into two groups of similar ages. The first group included 60 people with cutaneous leishmaniasis who were diagnosed by a doctor, in addition to a second group that included 30 people who were not infected with any disease as a control group. Cytokine concentrations were also measured using... ELISA technique, then statistical testing was performed. Results: showed high concentration of the cytokines that were under study interleukin 17 and interleukin 33 in the patient group compared to the group of control. Conclusions and recommendations: The increase in the level of cytokines in the patient group may indicate the role that these cytokines play in the regression of the disease Highlights: Cutaneous Leishmaniasis: Skin infection causing bumps, ulcers, slow healing. Study Groups: 60 patients, 30 controls, cytokines measured via ELISA. Findings: Elevated IL-17, IL-33 indicate cytokines' role in disease regression. Keywords: Cutaneous leishmaniasis, cytokines, interleukin-17, interleukin-33, ELISA
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