One of the most common health problems, especially in cases of non-communicable diseases, is diabetes mellitus. The prevalence of diabetes mellitus in urban areas reaches 1.3%. The purpose of this study was to analyze the factors that influence the incidence of diabetes mellitus in urban areas in Indonesia. This study was cross-sectional in nature. This study used secondary data from the 2023 SKI data with a sample size of 350,671 people aged ≥15 years throughout urban areas in Indonesia. The related variable was diabetes mellitus, and the independent variables were age, gender, nutritional status, blood pressure, and physical activity. The analyses used were complex sample chi-square and multiple logistic regression analysis. There was relationship with age (OR= 21.774; 95% CI: 19.172-24.730), gender (OR= 1.321; 95% CI: 1.244-1.402), nutritional status (OR= 1.523; 95% CI: 1.428-1.625), blood pressure (OR= 2.802; 95% CI: 2.641-2.973), and physical activity (OR= 1.409; 95% CI: 1.163-1.705) with the occurrence of diabetes mellitus. The most dominant factor was age (OR = 17.624; 95% CI: 15.493–20.048). Age >40 years, female gender, obese nutritional status, hypertension (≥140/90 mmHg), and low physical activity were risk factors, with age >40 years being the dominant factor in the incidence of diabetes mellitus.