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All Journal Jurnal Ilmu Kedokteran Keluarga Journal of Psychiatry Psychology and Behavioral Research (JPPBR)
Asmy, Hatimul
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Humanities Computer Science & IT Education Health Professions Medicine & Pharmacology Nursing Physics Public Health Social Sciences

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A 70-Year-Old Woman with Metabolic Syndrome and Rapid-Onset Diabetic Neuropathy Complications: The Role Risk Factor of Age, Gender, Underlying Desease, Lifestyle, and Medication Adherence Asmy, Hatimul; Noor Pratami, Gia; Rosita, Rita
Jurnal Ilmu Kedokteran Keluarga Vol. 3 No. 2: December 2024
Publisher : Family Medicine Department, Faculty of Medicine, Brawijaya University

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Abstract

Diabetic neuropathy is a symptom or sign of nerve dysfunction in patients with diabetes mellitus. This condition may occur when blood glucose levels remain uncontrolled for an extended period and could be triggered by several risk factors. In this case, the patient's condition was identified at a primary healthcare center in Malang City. Both medical and non-medical histories were explored to determine the involved risk factors, followed by two home visits to further assess and identify additional risk factors. This case report highlights the role of the family medicine approach, where the interaction of biopsychosocial variables necessitates holistic and comprehensive therapeutic.
OXYTOCIN IMPLICATION FOR SCHIZOPHRENIA FUTURE TREATMENT Asmy, Hatimul
Journal of Psychiatry Psychology and Behavioral Research Vol. 6 No. 2 (2025): Mental Health Framework from a Multidisciplinary Perspective
Publisher : Departemen Psikiatri Fakultas Kedokteran Universitas Brawijaya

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.21776/ub.jppbr.2025.006.02.5

Abstract

Introduction: Schizophrenia is a mental disorder, manifested as positive symptoms, negative symptoms, and cognitive dysfunction. Antipsychotic medication is given to treat schizophrenia; however, recently, antipsychotic medication is less effective in improving negative symptoms and cognitive deficits. Several neurotransmitters and neuropeptides are believed to be involved in the mechanism of schizophrenia, one of which is oxytocin. Methods: The author uses the literature review method with international journals limited to the period from 2014 to 2024 that discuss oxytocin as a treatment in schizophrenia patients. Results: Several results of studies showed that schizophrenia therapy using oxytocin improved negative symptoms and cognitive function in schizophrenia patients. These studies are based on previous research, which showed lower concentrations of oxytocin in schizophrenia patients. Discuss: Oxytocin acts as a human behavior regulator, and the oxytocinergic system is involved in the emergence of schizophrenia symptoms. Oxytocin administration through intranasal is chosen to deliver oxytocin because it reaches the central nervous system more easily. Oxytocin administration can improve oxytocin concentration in cerebrospinal fluid. Increasing oxytocin levels is significant in improving negative symptoms and cognitive function in schizophrenia patients. Conclusion: Oxytocin administration intranasally can increase oxytocin concentration to improve negative symptoms and cognitive function in schizophrenia patients.
Co-Authors Noor Pratami, Gia Rita Rosita