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All Journal Indonesian Journal of Pharmaceutical Science and Technology Jurnal Farmasi Klinik Indonesia
Nugrahaningtyas, Odilia Danti
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Computer Science & IT Medicine & Pharmacology

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Journal : Jurnal Farmasi Klinik Indonesia

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A Case Report: Risperidone-Induced Lactation Nonpuerperal in Bipolar Patient Rahajeng, Bangunawati; Maziyyah, Nurul; Nugrahaningtyas, Odilia Danti
Indonesian Journal of Clinical Pharmacy Vol 12, No 1 (2023)
Publisher : Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15416/ijcp.2023.12.1.60

Abstract

Risperidone is an atypical antipsychotic for acute and chronic schizophrenia and mania. In this case report, we report a rare side effect of risperidone, namely nonpuerperal lactation, where the common side effects of risperidone are insomnia, anxiety, headaches, and extrapyramidal symptoms. Lactation nonpuerperal is one of the rare side effects of risperidone, with an incidence in adults < 1%. We report the case of a 21-year-old woman. This woman was diagnosed with bipolar affective disorder with major depression and got risperidone, fluoxetine, trihexyphenidyl, and valproic acid for treatment. The first visit was at a teaching hospital on April 21, 2022. She had to control it within a month. At the first control on July 1, 2022, her condition improved. She had no complaints. On August 4, 2022, she came to the hospital and told the doctor that she had nonpuerperal lactation. We do a causality analysis that the side-effect is due to risperidone. From Naranjo’s analysis, we scored 6 for risperidone (probable). From the Liverpool algorithm, we concluded that risperidone probably caused lactation nonpuerperal. In this case, risperidone probably caused lactation nonpuerperal.
Co-Authors Nurul Maziyyah Rahajeng, Bangunawati