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Marsella, Virna Rindra
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Chemistry

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REVIEW ARTIKEL: IDENTIFIKASI FITOKIMIA, POTENSI AKTIVITAS ANTIOKSIDAN DAN TOKSISITAS DAUN BALAKACIDA (Chromolaena odorata L.) Marsella, Virna Rindra; Saleh, Chairul
PROSIDING SEMINAR KIMIA Vol 3 No 1 (2024): Prosiding SNK 2024
Publisher : Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

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Abstract

Balakacida is a plant that grows in open areas and thrives in plantations, so this plant is often referred to as a weed. This plant is often used as a live pharmaceutical plant to cure several diseases. Various studies on the phytochemical content of Balakacida plants have been conducted. Phytochemical identification of Balakacida plants shows that Balakacida plants contain phytochemical aglycones, flavonoids, terpenoids, essential oils, alkaloids, saponins, tannins and steroids. Literature studies show that Balakacida leaves have toxicity activity shown in the LC50 value. The LC50 values obtained in the crude extract, n-hexane fraction, ethyl acetate are 2.88 ppm, 8.12 ppm and 6.86 ppm respectively. It is known that Balakacida plants have high antioxidant content, this is influenced by its high flavonoid levels. In Balakacida leaf extract, having an IC50 value of 23.4 µg/mL. So that researchers can conclude that Balakacida leaf extract has phytochemical content of aglycone groups, flavonoids, terpenoids, essential oils, alkaloids, saponins, tannins and steroids, with very strong toxicity and antioxidant activity. Keywords: Antioxidant, Balakacida, phytochemical identification, toxicity
AKTIVITAS ANTIOKSIDAN DAN TOKSISITAS EKSTRAK ETHANOL DAUN BALAKACIDA (Chromolaena odorata L.) Marsella, Virna Rindra; Aswat, Muhammad Raihan; Erwin, Erwin
PROSIDING SEMINAR KIMIA Vol 3 No 2 (2025): Prosiding SNKT 2024
Publisher : Jurusan Kimia Fakultas Matematika dan Ilmu Pengetahuan Alam Universitas Mulawarman

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This study aims to determine the content of secondary metabolites and toxicity and antioxidants in Balakacida leaf (Chromolaena odorata L.). The dried Balakacida (Chromolaena odorata L.) leaf samples were extracted through maceration process using 96% ethanol solvent and the maceration filtrate was concentrated using rotary evaporator. Furthermore, the crude extract obtained was carried out phytochemical testing, toxicity test with BSLT method and antioxidant test with DPPH method. Phytochemical results of crude extracts of Balakacida leaf isolates (Chromolaena odorata L.) are positive for alkaloids, steroids, triterpenoids, flavonoids, phenolics and quinones. The results of the BSLT method toxicity test obtained an LC50 value of 42.77 ppm which indicates a very strong level of toxicity. The results of the antioxidant test obtained the actual IC50 value of 31.226 ppm indicate that the Balakacida leaf isolate (Chromolaena odorata L.) has very high antioxidant activity. Based on the results of the antioxidant test, Balakacida leaves (Chromolaena odorata L.) have potential as an antioxidant plant. Keywords : Antioxidant, Balakacida, Toxicity, Chromolaena odorata L
Co-Authors Aswat, Muhammad Raihan Chairul Saleh Erwin Erwin