One of the complications in the hemodialysis process is intradialysis hypertension. Hemodialysis patients also often experience increased interdialytic weight gain (IDWG). IDWG and intradialysis hypertension are each associated with patient mortality and morbidity. This study was conducted to determine the relationship between interdialytic weight gain and intradialysis hypertension in hemodialysis patients at Depok City Hospital. This research method is quantitative with cross sectional design. A total of 92 hemodialysis patients who met the inclusion criteria were selected using purposive sampling technique. Data were collected using a respondent characteristics questionnaire, IDWG scoring sheet, and intradialysis systolic blood pressure observation sheet. The results showed that 37% of respondents were 55-64 years old; 53.3% were female; 48.9% had a high school education; 76.1% of respondents did not work; 75% of respondents had an economic status of