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All Journal International Journal of Integrated Health Sciences Canrea Journal: Food Technology, Nutritions, and Culinary Journal
Ghosh, Arindam
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Agriculture, Biological Sciences & Forestry Health Professions

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Prevalence of Thyroid Function Abnormalities and Its Association with Physical Fatigue in First-Year Medical Students Ghosh, Arindam; Dasgupta, Debdeep; Biswas, Susumna
International Journal of Integrated Health Sciences Vol 12, No 2 (2024)
Publisher : Faculty of Medicine Universitas Padjadjaran

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.15850/ijihs.v12.n2.4087

Abstract

Objective: To estimate prevalence and type of thyroid function abnormalities and explore their associations with physical fatigue in first-year medical students.Methods: This was a cross-sectional observational study comprising of 200 first-year medical students.  Demographic details and history of any significant medical illness was asked and noted. Thyroid function tests were conducted on all participants. The prevalence and type of thyroid function abnormalities were documented in all students,  and the presence and severity of physical fatigue were assessed on the basis of physical fatigue score. Participants with any kind of thyroid function abnormality were compared with those with normal thyroid function tests for presence and severity of fatigue.Results: Among the 200 students, 144 (72%) were males and 56 (28%) were females, resulting in a male-to-female ratio of 1:0.38. Subclinical hypothyroidism was identified in 9% of students (18 cases), while clinical hypothyroidism was present in 7% (14 cases). Additionally, subclinical hyperthyroidism was detected in 1% of students (2 cases), with no cases of clinical hyperthyroidism reported. Female students were found to be having more thyroid function abnormalities as compared to male students and the difference was found to be statistically significant (p=0.0109).  Students with abnormal thyroid function tests (34 cases) had a markedly higher mean FSS score (43.22±4.50) as compared to students with euthyroid (16.85±2.70).Conclusion: Subclinical thyroid abnormalities are prevalent among young individuals, particularly those with physical fatigue. This study revealed a significant link between presence of fatigue and the possibility of thyroid dysfunction.
In vitro bioactivities and simulated gastrointestinal digestion studies on Guras-based traditional fermented drinks collected from Singalila ridge of the Himalayas Majumder, Soumya; Ghosh, Arindam; Bhattacharya, Malay
jurnal1 VOLUME 6 ISSUE 2, DECEMBER 2023
Publisher : Hasanuddin University Food Science and Technology Study Program

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.20956/canrea.v6i2.1125

Abstract

Guras or Rhododendron wine and its distilled form (Raksi) are popular traditional and therapeutic drinks served in the Rhododendron growing regions of the Himalayas, mainly in the northern and northeastern part of India, Nepal and Indo-Nepal Singalila ridge. In this research, lali Guras (Rhododendron arboreum Sm.) based traditional beverages such as unfermented decoction (as control), fermented Guras wine and distilled spirit Guras ko Raksi were collected from Singalila ridge of the Himalayas for analysis. In vitro experiments such as physicochemical and qualitative and quantitative biochemical tests; antioxidant assays (DPPH and iodometric assay); antibacterial assay; and simulated gastrointestinal digestion were carried out. Phytochemically rich unfermented decoction exhibited the best results in total phenolic content assay (82.18±1.13 mg/100 mL gallic acid equivalent) and fatty acid quantification (1.86±0.08%) test while the wine was found to be the most potential sample in all bioactivity tests. The wine was found to contain high amounts of glycoside and fermented distilled liquor Guras Raksi showed high presence of glycerol. Both the fermented samples exhibited high rate of digestion in simulated human digestion system compared to the phenolic rich unfermented decoction. This research validated the therapeutic potential of these Guras-based beverages in high-altitude conditions like Singalila by focusing on their biochemistry.
Co-Authors Bhattacharya, Malay Biswas, Susumna Dasgupta, Debdeep Majumder, Soumya